Findings

What do systematic reviews say?

189 questions · 190 findings · 12 reviews · Eyes and Vision

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No studies found 57 · 30%GRADE not reported 4 · 2.1%Very low 53 · 27.9%Low 33 · 17.4%Moderate 28 · 14.7%High 15 · 7.9%

Summary of findings: acrylic vs silicone punctal plugs

Symptomatic improvement · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings: acrylic vs silicone punctal plugs

Ocular surface staining · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings: acrylic vs silicone punctal plugs

Aqueous tear production · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings: acrylic vs silicone punctal plugs

Tear film stability · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings: acrylic vs silicone punctal plugs

Artificial tear use · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings: acrylic vs silicone punctal plugs

Adverse events · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings table ‐ Collagen vs silicone punctal plugs

Symptomatic improvement · adults with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings table ‐ Collagen vs silicone punctal plugs

Ocular surface staining · adults with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings table ‐ Collagen vs silicone punctal plugs

Aqueous tear production · adults with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings table ‐ Collagen vs silicone punctal plugs

Tear film stability · adults with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings table ‐ Collagen vs silicone punctal plugs

Artificial tear use · adults with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Summary of findings table ‐ Collagen vs silicone punctal plugs

Adverse events · adults with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings for NSAIDs vs corticosteroids

Intraocular inflammation measured by anterior chamber cell and flare 1 week · people who received phacoemulsification

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 174 participants
Moderate

Summary of findings for NSAIDs vs corticosteroids

Intraocular inflammation measured by proportion of participants with corneal edema 1 week · people who received phacoemulsification

Summary of findings for NSAIDs showed no clear difference in intraocular inflammation measured by proportion of participants with… compared with corticosteroids (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
RR 0.77 [0.26, 2.29]
1 study · 114 participants
Low

Summary of findings for NSAIDs vs corticosteroids

Proportion of participants with best‐corrected visual acuity of 20/40 1 week · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs vs corticosteroids

Proportion of participants with cystoid macular edema 1 week · people who received phacoemulsification

Summary of findings for NSAIDs may leads to lower proportion of participants with cystoid macular edema 1 week compared with corticosteroids (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
RR 0.26 [0.17, 0.41]
4 studies · 291 participants
Low

Summary of findings for NSAIDs vs corticosteroids

Time to cessation of treatment · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs vs corticosteroids

Adverse events · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs vs corticosteroids

Economic outcomes · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: bevacizumab vs ranibizumab

Mean change in visual acuity at 1 year (number of letters) · people with neovascular age‐related macular degeneration

Summary of findings: bevacizumab showed no clear difference in mean change in visual acuity at 1 year (number of letters) compared with ranibizumab (high certainty).

1 finding from 1 review

Anti‐vascular endothelial growth factor for neovascular age‐related macular degeneration 2019 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 3190 participants
High