Relapse: return to any drinking at end of treatment · alcohol use disorder
Summary of findings table ‐ Baclofen probably leads to lower relapse: return to any drinking at end of treatment compared with placebo (moderate certainty).
1 finding from 1 review
Dropout · alcohol use disorder
It is very uncertain whether summary of findings table ‐ Baclofen changes dropouts at end of treatment compared with acamprosate (very low certainty).
1 finding from 1 review
Dropouts due to adverse events · alcohol use disorder
It is very uncertain whether summary of findings table ‐ Baclofen changes dropouts due to adverse events compared with acamprosate (very low certainty).
1 finding from 1 review
Relapse: return to any drinking at end of treatment · alcohol use disorder
It is very uncertain whether summary of findings table ‐ Baclofen changes relapse: return to any drinking at end of treatment compared with naltrexone (very low certainty).
1 finding from 1 review
Adverse events: number of participants with ≥ 1 adverse event at end of treatment · alcohol use disorder
It is very uncertain whether summary of findings table ‐ Baclofen changes adverse events: number of participants with ≥ 1 adverse event at end… compared with naltrexone (very low certainty).
1 finding from 1 review
Dropout · alcohol use disorder
It is very uncertain whether summary of findings table ‐ Baclofen changes dropouts at end of treatment compared with naltrexone (very low certainty).
1 finding from 1 review
Frequency of use % days abstinence at the end of treatment · alcohol use disorder
1 finding from 1 review
Frequency of use % of heavy drinking days at the end of treatment · alcohol use disorder
1 finding from 1 review
Amount of use drink per drinking days at the end of treatment · alcohol use disorder
1 finding from 1 review
Adverse events: number of participants with ≥ 1 adverse event at end of treatment · alcohol use disorder
Summary of findings table ‐ Baclofen showed no clear difference in adverse events: number of participants with ≥ 1 adverse event at end… compared with placebo (high certainty).
1 finding from 1 review
Dropout · alcohol use disorder
Summary of findings table ‐ Baclofen showed no clear difference in dropouts at end of treatment compared with placebo (high certainty).
1 finding from 1 review
Dropouts due to adverse events · alcohol use disorder
Summary of findings table ‐ Baclofen showed no clear difference in dropouts due to adverse events compared with placebo (high certainty).
1 finding from 1 review
Relapse: return to any drinking at end of treatment · alcohol use disorder
It is very uncertain whether summary of findings table ‐ Baclofen changes relapse: return to any drinking at end of treatment compared with acamprosate (very low certainty).
1 finding from 1 review
Adverse events as N of participants with at least one adverse event subjective and objective · alcohol use disorder
It is very uncertain whether summary of findings table ‐ Baclofen changes adverse events: number of participants with at least one adverse… compared with acamprosate (very low certainty).
1 finding from 1 review
Frequency of cocaine use (mean number of days or weeks of cocaine use at the end of treatment) · patients with the treatment of cocaine dependence
1 finding from 1 review
Continuous abstinence from cocaine (number of participants who had achieved and maintained abstinence for at least three weeks at the end of treatment) · patients with the treatment of cocaine dependence
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Point abstinence (number of participants who were abstinent at the end of the treatment) · patients with the treatment of cocaine dependence
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acceptability ‐ total dropouts · patients with the treatment of cocaine dependence
It is very uncertain whether summary of findings table – disulfiram changes dropout for any reason (number of participants who did not complete… compared with naltrexone (very low certainty).
1 finding from 1 review
Dropouts due to adverse events · patients with the treatment of cocaine dependence
It is very uncertain whether summary of findings table – disulfiram changes dropout due to adverse events (number of participants who did not… compared with naltrexone (very low certainty).
1 finding from 1 review
RR 0.5 [0.07, 3.55]
1 study · 8 participants
Very low
Adverse events as N of participants with at least one adverse event objective · patients with the treatment of cocaine dependence
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found