Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

90 questions · 97 findings · 9 reviews · Skin

No studies found 25 · 25.8%GRADE not reported 4 · 4.1%Very low 15 · 15.5%Low 34 · 35.1%Moderate 18 · 18.6%High 1 · 1%

Corticosteroids vs no corticosteroid use

Disease‐specific mortality ‐ SJS and TEN (time to · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome

It is very uncertain whether corticosteroids changes disease‐specific mortality ‐ SJS and TEN (time to compared with no corticosteroids (very low certainty).

1 finding from 1 review

Corticosteroids vs no corticosteroid use

Adverse effects leading to discontinuation of SJT/TEN therapy ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome

The review found no eligible studies for this question.

1 finding from 1 review