Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

170 questions · 174 findings · 17 reviews · Headline outcomes only

No studies found 51 · 29.3%GRADE not reported 30 · 17.2%Very low 22 · 12.6%Low 38 · 21.8%Moderate 22 · 12.6%High 11 · 6.3%

High‐dose chemotherapy vs chemotherapy without bone marrow transplant or stem cell rescue

Overall survival at 5‐year · women with early poor prognosis breast cancer

High‐dose chemotherapy showed no clear difference in overall survival at 5‐year compared with chemotherapy without bone marrow transplant or stem cell rescue (high certainty).

1 finding from 1 review