Treatment failure (annual failure rate) by cavity class · Children with carious primary teeth restored in Class-I versus Class-II cavities, no pulp therapy
Class-II restorations failed more than Class-I (annual failure 5-28.9% vs 1.2-14.7% in ART studies); low quality of evidence (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
Hemostasis within 6 min gave the highest success (90.4%), but the difference across hemostasis-time groups was not significant (ungraded).
13 findings from 1 review
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Proportion 0.856
Studies not reported
GRADE not reported
Proportion 0.862
Studies not reported
GRADE not reported
Proportion 0.824 [0.746, 0.890]
Studies not reported
GRADE not reported
Proportion 0.909 [0.833, 0.965]
Studies not reported
GRADE not reported
Proportion 0.882
Studies not reported
GRADE not reported
Proportion 0.867 [0.820, 0.907]
25 studies · 2012 participants
Very low
Proportion 0.902
Studies not reported
GRADE not reported
Proportion 0.838 [0.759, 0.904]
Studies not reported
GRADE not reported
Proportion 0.872 [0.803, 0.929]
Studies not reported
GRADE not reported
Proportion 0.859
Studies not reported
GRADE not reported
Pulp necrosis · Vital teeth restored with indirect restorations
Pulp necrosis incidence among treated by prosthodontists was 1.87% (subgroup analysis; not GRADE-rated).
23 findings from 1 review
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Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Temporization >2 weeks
Proportion 4.25 [1.28, 8.85]
2280 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomes>10 years · University clinics and dental practices, multiple countries · Follow-up >10 years
Proportion 6.74 [2.82, 12.18]
3640 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Temporization ≤2 weeks
Proportion 1.47 [0.81, 2.31]
1907 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Radiographic pulp-status assessment
Proportion 4.95 [2.43, 8.29]
1853 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Polyvinyl siloxane impression material
Proportion 3.17 [1.55, 5.34]
636 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Resin permanent cement
Proportion 3.37 [1.90, 5.23]
738 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Eugenol-based temporary cement
Proportion 3.34 [1.66, 5.58]
7043 participants
GRADE not reported
Proportion 3.53 [2.10, 5.31]
5532 participants
GRADE not reported
Proportion 5.02 [3.70, 6.52]
37 studies · 11615 participants
Low
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Treated by general practitioners
Proportion 4.44 [2.16, 7.49]
2113 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Single-unit restorations
Proportion 5.46 [3.63, 7.64]
20 studies · 5491 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Zinc phosphate permanent cement
Proportion 4.92 [3.85, 6.20]
1387 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Polyether impression material
Proportion 4.02 [2.47, 5.92]
2985 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Ceramic fabrication material
Proportion 5.59 [2.89, 9.12]
460 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Subjective pulp-status assessment
Proportion 3.91 [1.86, 6.66]
3181 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Eugenol-free temporary cement
Proportion 5.77 [3.72, 8.24]
639 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Treated by undergraduate students
Proportion 5.68 [3.17, 8.86]
1604 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Glass ionomer (GIC) permanent cement
Proportion 5.33 [2.56, 9.03]
182 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Objective pulp-status assessment
Proportion 5.66 [3.71, 7.99]
6581 participants
GRADE not reported
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a… 2023 All outcomesFollow-up ≤5 to >10 years · University clinics and dental practices, multiple countries · Fixed partial dentures (FPD)
Proportion 5.01 [2.76, 7.88]
15 studies · 4674 participants
GRADE not reported
Periapical pathosis · Vital teeth restored with indirect restorations
Periapical pathosis incidence among follow-up >5-10 years was 3.88% (subgroup analysis; not GRADE-rated).
6 findings from 1 review
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Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
Among 6 observational studies, pooled pulpotomy success was 92.6 per 100 (95% CI 0.86-0.96), very low certainty.
4 findings from 1 review
Show 1 more finding
Overall success (composite of clinical and radiographic success) · Human permanent teeth with asymptomatic irreversible pulpitis due to carious pulp exposure
In asymptomatic irreversible pulpitis, pooled pulpotomy success was 91.3% (95% CI 80-96.5%); ungraded.
1 finding from 1 review
Treatment failure (annual failure rate) · Children with carious primary teeth treated by atraumatic restorative treatment (hand-instrument caries removal), no pulp therapy
ART restorations (mainly GIC) had a wide annual failure rate (1.2-37.1%) across 10 RCTs, with technique affecting survival; low to unclear quality of evidence (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis and open (immature) root apex due to carious pulp exposure
In open-apex teeth, pooled pulpotomy success was 95.8% (95% CI 81-99%); significantly higher than closed apex (z=2.33, p=0.02); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis and closed (mature) root apex due to carious pulp exposure
In closed-apex teeth, pooled pulpotomy success was 83% (95% CI 69-91%); significantly lower than open apex (z=2.33, p=0.02); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with symptomatic irreversible pulpitis due to carious pulp exposure
In symptomatic irreversible pulpitis, pooled pulpotomy success was 84% (95% CI 72-92%); not significantly different from asymptomatic (z=-1.34, p=0.18); ungraded.
1 finding from 1 review