Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

65 questions · 81 findings · 3 reviews · All outcomes

No studies found 35 · 43.2%GRADE not reported 7 · 8.6%Very low 34 · 42%Low 4 · 4.9%Moderate 1 · 1.2%High 0 · 0%

Silver diamine fluoride (SDF) vs Silver nitrate plus fluoride varnish

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Silver diamine fluoride (SDF) vs Silver nitrate plus fluoride varnish

Caries arrest · Children and adults (with or without carious lesions)

Silver diamine fluoride (SDF) showed no clear difference in caries arrest compared with silver nitrate plus fluoride varnish (low certainty).

1 finding from 1 review

Silver diamine fluoride (SDF) vs Sealants or resin infiltration

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Silver diamine fluoride (SDF) vs Atraumatic restorative treatment (ART) with glass ionomer cement (GIC) or glass ionomer material

Dental pain or sensitivity · Children and adults (with or without carious lesions)

It is very uncertain whether silver diamine fluoride (SDF) changes dental pain or sensitivity compared with atraumatic restorative treatment (ART) with glass ionomer cement… (very low certainty).

1 finding from 1 review

Silver diamine fluoride (SDF) vs Atraumatic restorative treatment (ART) with glass ionomer cement (GIC) or glass ionomer material

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Silver diamine fluoride (SDF) vs placebo or no treatment

Caries arrest · Children and adults (with or without carious lesions)

It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with placebo or no treatment (very low certainty).

3 findings from 1 review

Silver diamine fluoride (SDF) vs Sealants or resin infiltration

Secondary prevention of caries · Children and adults (with or without carious lesions)

Silver diamine fluoride (SDF) showed no clear difference in secondary prevention of caries compared with sealants or resin infiltration; GRADE not reported.

1 finding from 1 review

Silver diamine fluoride (SDF) vs Restoration (restorative treatment)

Aesthetics · Children and adults (with or without carious lesions)
1 finding from 1 review