Question · asked by 1 review
Silver diamine fluoride (SDF) vs placebo or no treatment: Caries arrest
- Population
- Children and adults (with or without carious lesions)
- Intervention
- Silver diamine fluoride (SDF)
- Comparison
- placebo or no treatment
- Outcome
- Caries arrest
It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with placebo or no treatment (very low certainty).
What each review found
Include earlier review versionsNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Silver diamine fluoride (SDF) vs Placebo or no treatment Caries arrest · Children and adults (with or without carious lesions) · 36 months, Permanent dentition (coronal) It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with placebo or no treatment (very low certainty). Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults (2024) · Cochrane All outcomes | MD 0.20 [0.00, 0.40] | 1 study · 373 participants | Very low |
Silver diamine fluoride (SDF) vs Placebo or no treatment Caries arrest · Children and adults (with or without carious lesions) · 24 months, Permanent dentition (root) It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with placebo or no treatment (very low certainty). Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults (2024) · Cochrane All outcomes | MD 0.24 [0.12, 0.36] | 1 study · 158 participants | Very low |
Silver diamine fluoride (SDF) vs Placebo or no treatment Caries arrest · Children and adults (with or without carious lesions) · 24 to 36 months, Primary dentition Silver diamine fluoride (SDF) may leads to higher caries arrest compared with placebo or no treatment (low certainty). Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults (2024) · Cochrane All outcomes | MD 0.86 [0.39, 1.33] | 2 studies · 841 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes | 2023-06 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Silver diamine fluoride (SDF) vs Fluoride varnish · Children and adults (with or without carious lesions) · 1 review
- Silver diamine fluoride (SDF) vs Atraumatic restorative treatment (ART) with glass ionomer cement (GIC) or glass ionomer material · Children and adults (with or without carious lesions) · 1 review
- Silver diamine fluoride (SDF) vs Restoration (restorative treatment) · Children and adults (with or without carious lesions) · 1 review
- Silver diamine fluoride (SDF) vs Silver nitrate plus fluoride varnish · Children and adults (with or without carious lesions) · 1 review
- Silver diamine fluoride (SDF) vs Glass ionomer cement (GIC) plus fluoride varnish · Children and adults (with or without carious lesions) · 1 review
- Silver diamine fluoride (SDF) vs Sealants or resin infiltration · Children and adults (with or without carious lesions) · 1 review
- Silver diamine fluoride (SDF) vs Chlorhexidine varnish · Children and adults (with or without carious lesions) · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.