Paraesthesia · women with operable primary breast cancer
Sentinel node biopsy may leads to lower paraesthesia compared with full axillary surgery (low certainty).
1 finding from 1 review
Pain · women with operable primary breast cancer
Sentinel node biopsy may leads to lower pain compared with full axillary surgery (low certainty).
1 finding from 1 review
Numbness · women with operable primary breast cancer
Sentinel node biopsy probably leads to lower numbness compared with full axillary surgery (moderate certainty).
1 finding from 1 review
All‐cause mortality · women with operable primary breast cancer
Sentinel node biopsy showed no clear difference in all‐cause mortality compared with full axillary surgery (moderate certainty).
1 finding from 1 review
Lymphoedema Patient‐reported lymphoedema of any severity · women with operable primary breast cancer
Sentinel node biopsy may leads to lower lymphoedema Patient‐reported lymphoedema of any severity compared with full axillary surgery (low certainty).
1 finding from 1 review
Subjective arm movement impairment · women with operable primary breast cancer
It is very uncertain whether sentinel node biopsy changes subjective arm movement impairment compared with full axillary surgery (very low certainty).
1 finding from 1 review
Recurrence · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Recurrence: Garrel 2020 reported that the number of patients with recurrences in both arms was almost identical; unable to use the data (variable follow-up); 279 participants (1 RCT).
1 study · 279 participants
Very low
Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer
Sentinel node biopsy (neck dissection only if biopsy positive) showed no clear difference in locoregional recurrence compared with elective neck dissection (low certainty).
1 finding from 1 review
Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Total mortality · Adults with oral cavity or oropharyngeal cancer
Sentinel node biopsy (neck dissection only if biopsy positive) showed no clear difference in total mortality compared with elective neck dissection (low certainty).
1 finding from 1 review
Disease-free survival · Adults with oral cavity or oropharyngeal cancer
Sentinel node biopsy (neck dissection only if biopsy positive) showed no clear difference in disease-free survival (new disease, progression, and mortality) compared with elective neck dissection (low certainty).
1 finding from 1 review
Overall Survival Intention‐to‐treat Death from any cause during the study · patients with localised primary cutaneous melanoma
SLNB showed no clear difference in overall Survival Intention‐to‐treat Death from any cause during the… compared with observation (low certainty).
1 finding from 1 review
Surgical Morbidity (Within 30 d) Related to the Regional Nodal Basin in Patients Assigned to the 2 Treatment Arms of MSLT‐I Any complication in the dissected basin, regional or systemic related to the surgical treatment in the regional nodal basin · patients with localised primary cutaneous melanoma
SLNB may leads to higher surgical Morbidity (Within 30 d) Related to the Regional Nodal Basin… compared with observation (low certainty).
1 finding from 1 review
Surgical Morbidity (Within 30 d) Related to Wide Excision of the Primary Site in Patients Assigned to the 2 Treatment Arms of MSLT‐I Any Surgical Complication related to the wide excision site · patients with localised primary cutaneous melanoma
SLNB showed no clear difference in surgical Morbidity (Within 30 d) Related to Wide Excision of the… compared with observation (low certainty).
1 finding from 1 review
Disease‐specific Survival Death from melanoma · patients with localised primary cutaneous melanoma
SLNB showed no clear difference in disease‐specific Survival Death from melanoma compared with observation (low certainty).
1 finding from 1 review
Disease‐free Survival First pathologically confirmed recurrence · patients with localised primary cutaneous melanoma
SLNB may leads to lower disease‐free Survival First pathologically confirmed recurrence compared with observation (low certainty).
1 finding from 1 review
Locoregional recurrence · patients with localised primary cutaneous melanoma
SLNB may leads to lower rate of pathologically confirmed locoregional recurrence following… compared with observation (low certainty).
1 finding from 1 review
Rate of development of distant metastases following SLNB and curative CLND First pathologically confirmed distant metastasis · patients with localised primary cutaneous melanoma
SLNB may leads to higher rate of development of distant metastases following SLNB and… compared with observation (low certainty).
1 finding from 1 review