Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 20%Low 3 · 30%Moderate 5 · 50%High 0 · 0%

Sealant + 5% NaF varnish vs Sealant

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

Sealant + 5% NaF varnish was probably more effective than Sealant for arrest or reversal of occlusal carious lesions (RR 1.69, 95% CI 1.26 to 2.27; moderate certainty).

1 finding from 1 review

Sealant + 5% NaF varnish vs no treatment

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

Sealant + 5% NaF varnish was probably more effective than no treatment for arrest or reversal of occlusal carious lesions (RR 3.35, 95% CI 2.42 to 4.64; moderate certainty).

1 finding from 1 review

Fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

5% NaF varnish was probably less effective than Sealant + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.59, 95% CI 0.45 to 0.76; moderate certainty).

1 finding from 1 review

Resin infiltration + 5% NaF varnish vs Sealants plus fluoride varnish (with or without restorations)

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

Resin infiltration + 5% NaF varnish may not differ from Sealant + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.95, 95% CI 0.75 to 1.21; low certainty).

1 finding from 1 review

Fluoride varnish vs Sealant

Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)

5% NaF varnish may not differ from Sealant for arrest or reversal of approximal carious lesions (RR 0.95, 95% CI 0.38 to 2.41; very low certainty).

1 finding from 1 review

Fluoride varnish vs Sealant

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

5% NaF varnish may not differ from Sealant for arrest or reversal of occlusal carious lesions (RR 0.99, 95% CI 0.86 to 1.15; low certainty).

1 finding from 1 review

Resin infiltration + 5% NaF varnish vs Sealant

Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)

Resin infiltration + 5% NaF varnish may not differ from Sealant for arrest or reversal of approximal carious lesions (RR 1.91, 95% CI 0.48 to 7.52; very low certainty).

1 finding from 1 review

Resin infiltration + 5% NaF varnish vs Sealant

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

Resin infiltration + 5% NaF varnish was probably more effective than Sealant for arrest or reversal of occlusal carious lesions (RR 1.61, 95% CI 1.16 to 2.24; moderate certainty).

1 finding from 1 review

0.2% NaF mouthrinse + supervised toothbrushing vs Sealants plus fluoride varnish (with or without restorations)

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

0.2% NaF mouthrinse + supervised toothbrushing was probably less effective than Sealant + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.58, 95% CI 0.43 to 0.79; moderate certainty).

1 finding from 1 review

1.23% APF gel vs Sealants plus fluoride varnish (with or without restorations)

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

1.23% APF gel may be less effective than Sealant + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.64, 95% CI 0.44 to 0.92; low certainty).

1 finding from 1 review