Findings

What do systematic reviews say?

13 questions · 20 findings · 1 reviews · Periodontology

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No studies found 0 · 0%GRADE not reported 20 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Salvadora persica (miswak) mouthrinse vs Chlorhexidine mouthrinse

Plaque · Medically healthy individuals (adults and children, 6-60 years)

When usual mechanical plaque control continued, Salvadora persica and chlorhexidine did not differ significantly for plaque; not GRADE-rated.

8 findings from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-intervention · In vivo clinical trial (human oral cavity) · Did not refrain from mechanical plaque control
MD 0.17 [-0.08, 0.42]
11 studies · 594 participants
GRADE not reported
The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-intervention · In vivo clinical trial (human oral cavity) · Duration of mouthwash use: >=3 weeks
MD 0.24 [-0.11, 0.60]
7 studies · 420 participants
GRADE not reported
The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-intervention · In vivo clinical trial (human oral cavity)
MD 0.19 [0.01, 0.37]
18 studies · 902 participants
GRADE not reported

Show 5 more findings

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-intervention · In vivo clinical trial (human oral cavity) · Refrained from mechanical plaque control
MD 0.22 [0.05, 0.39]
7 studies · 308 participants
GRADE not reported
The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-intervention · In vivo clinical trial (human oral cavity) · Study quality: moderate-quality studies
MD 0.19 [-0.11, 0.50]
10 studies · 616 participants
GRADE not reported
The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-intervention · In vivo clinical trial (human oral cavity) · Duration of mouthwash use: <3 weeks
MD 0.15 [0.01, 0.29]
11 studies · 482 participants
GRADE not reported
The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-intervention · In vivo clinical trial (human oral cavity) · Chlorhexidine concentration: 0.12%
MD 0.52 [0.35, 0.69]
5 studies · 396 participants
GRADE not reported
The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-intervention · In vivo clinical trial (human oral cavity) · Study quality: high-quality studies
MD 0.19 [0.06, 0.31]
8 studies · 286 participants
GRADE not reported

Salvadora persica (miswak) mouthrinse vs Chlorhexidine 0.2% mouthrinse

Plaque · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica was less effective than 0.2% chlorhexidine at reducing plaque (favours chlorhexidine); not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-intervention · In vivo clinical trial (human oral cavity) · Chlorhexidine concentration: 0.2%
MD 0.12 [0.03, 0.21]
12 studies · 566 participants
GRADE not reported

Salvadora persica (miswak) mouthrinse vs Pre-treatment (baseline, same group)

Lactobacillus count (pre- vs post-treatment) · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica rinse reduced Lactobacillus counts relative to baseline; not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Pre- vs post-treatment · In vivo clinical trial (human oral cavity)
MD 1.54 [0.91, 2.17]
2 studies · 30 participants
GRADE not reported

Salvadora persica (miswak) mouthrinse vs Placebo rinse

Lactobacillus count (CFU/mL) · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica rinse reduced Lactobacillus counts more than placebo (favours Salvadora persica); not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-treatment · In vivo clinical trial (human oral cavity)
MD -1.12 [-1.45, -0.79]
2 studies · 60 participants
GRADE not reported

Salvadora persica (miswak) mouthrinse vs Pre-treatment (baseline, same group)

Streptococcus mutans count · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica rinse reduced Streptococcus mutans counts relative to baseline; not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Pre- vs post-treatment · In vivo clinical trial (human oral cavity)
MD 1.82 [1.03, 2.62]
5 studies · 71 participants
GRADE not reported

Salvadora persica (miswak) mouthrinse vs Placebo rinse

Streptococcus mutans count · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica rinse reduced Streptococcus mutans counts more than placebo (favours Salvadora persica); not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-treatment · In vivo clinical trial (human oral cavity)
MD -1.42 [-2.08, -0.76]
5 studies · 142 participants
GRADE not reported

Salvadora persica (miswak) mouthrinse vs Placebo rinse

Plaque · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica rinse reduced plaque more than placebo (favours Salvadora persica); certainty not GRADE-rated (Shekelle grade Ia).

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Post-intervention · In vivo clinical trial (human oral cavity)
MD -0.59 [-0.82, -0.35]
12 studies · 452 participants
GRADE not reported

Salvadora persica (miswak) mouthrinse vs Pre-treatment (baseline, same group)

Plaque · Medically healthy individuals (adults and children, 6-60 years)

Salvadora persica rinse reduced plaque relative to its own baseline; not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Pre- vs post-treatment · In vivo clinical trial (human oral cavity)
MD 0.46 [0.29, 0.63]
12 studies · 310 participants
GRADE not reported

Chlorhexidine 0.2% vs Pre-treatment (baseline, same group)

Plaque · Medically healthy individuals (adults and children, 6-60 years)

0.2% chlorhexidine rinse reduced plaque relative to baseline; not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Pre- vs post-treatment · In vivo clinical trial (human oral cavity) · Chlorhexidine concentration: 0.2%
MD 0.45 [0.19, 0.70]
10 studies · 282 participants
GRADE not reported

Chlorhexidine 0.12% mouthrinse vs Pre-treatment (baseline, same group)

Plaque · Medically healthy individuals (adults and children, 6-60 years)

0.12% chlorhexidine rinse reduced plaque relative to baseline; not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Pre- vs post-treatment · In vivo clinical trial (human oral cavity) · Chlorhexidine concentration: 0.12%
MD 1.79 [1.39, 2.19]
2 studies · 126 participants
GRADE not reported

Placebo rinse vs Pre-treatment (baseline, same group)

Lactobacillus count (pre- vs post-treatment) · Medically healthy individuals (adults and children, 6-60 years)

Placebo rinse did not significantly change Lactobacillus counts relative to baseline; not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Pre- vs post-treatment · In vivo clinical trial (human oral cavity)
MD 0.34 [-0.50, 1.18]
2 studies · 30 participants
GRADE not reported

Placebo rinse vs Pre-treatment (baseline, same group)

Plaque · Medically healthy individuals (adults and children, 6-60 years)

Placebo rinse did not significantly change plaque relative to baseline; not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Pre- vs post-treatment · In vivo clinical trial (human oral cavity)
MD -0.19 [-0.39, 0.02]
7 studies · 152 participants
GRADE not reported

Placebo rinse vs Pre-treatment (baseline, same group)

Streptococcus mutans count · Medically healthy individuals (adults and children, 6-60 years)

Placebo rinse did not significantly change Streptococcus mutans counts relative to baseline; not GRADE-rated.

1 finding from 1 review

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… 2019 All outcomes
Pre- vs post-treatment · In vivo clinical trial (human oral cavity)
MD 0.34 [-0.07, 0.76]
5 studies · 71 participants
GRADE not reported