Question · asked by 1 review
Salvadora persica (miswak) mouthrinse vs Chlorhexidine mouthrinse: Plaque
- Population
- Medically healthy individuals (adults and children, 6-60 years)
- Intervention
- Salvadora persica (miswak) mouthrinse
- Comparison
- Chlorhexidine mouthrinse
- Outcome
- Plaque
When usual mechanical plaque control continued, Salvadora persica and chlorhexidine did not differ significantly for plaque; not GRADE-rated.
What each review found
Include earlier review versionsNo studies found 0 · 0%GRADE not reported 8 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Salvadora persica (miswak) mouthrinse vs Chlorhexidine mouthrinse Post-intervention mean plaque score · Medically healthy individuals (adults and children, 6-60 years) · Post-intervention, In vivo clinical trial (human oral cavity), Did not refrain from mechanical plaque control When usual mechanical plaque control continued, Salvadora persica and chlorhexidine did not differ significantly for plaque; not GRADE-rated. The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… (2019) All outcomes | MD 0.17 [-0.08, 0.42] | 11 studies · 594 participants | GRADE not reported |
Salvadora persica (miswak) mouthrinse vs Chlorhexidine mouthrinse Post-intervention mean plaque score · Medically healthy individuals (adults and children, 6-60 years) · Post-intervention, In vivo clinical trial (human oral cavity), Duration of mouthwash use: >=3 weeks For use of 3 weeks or longer, Salvadora persica and chlorhexidine did not differ significantly for plaque reduction; not GRADE-rated. The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… (2019) All outcomes | MD 0.24 [-0.11, 0.60] | 7 studies · 420 participants | GRADE not reported |
Salvadora persica (miswak) mouthrinse vs Chlorhexidine mouthrinse Post-intervention mean plaque score · Medically healthy individuals (adults and children, 6-60 years) · Post-intervention, In vivo clinical trial (human oral cavity) Salvadora persica rinse was slightly less effective than chlorhexidine at reducing plaque (favours chlorhexidine); certainty not GRADE-rated (Shekelle grade Ia). The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… (2019) All outcomes | MD 0.19 [0.01, 0.37] | 18 studies · 902 participants | GRADE not reported |
Salvadora persica (miswak) mouthrinse vs Chlorhexidine mouthrinse Post-intervention mean plaque score · Medically healthy individuals (adults and children, 6-60 years) · Post-intervention, In vivo clinical trial (human oral cavity), Refrained from mechanical plaque control When mechanical plaque control was withheld, chlorhexidine outperformed Salvadora persica for plaque reduction; not GRADE-rated. The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… (2019) All outcomes | MD 0.22 [0.05, 0.39] | 7 studies · 308 participants | GRADE not reported |
Salvadora persica (miswak) mouthrinse vs Chlorhexidine mouthrinse Post-intervention mean plaque score · Medically healthy individuals (adults and children, 6-60 years) · Post-intervention, In vivo clinical trial (human oral cavity), Study quality: moderate-quality studies In moderate-quality studies the plaque difference between Salvadora persica and chlorhexidine was not statistically significant; not GRADE-rated. The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… (2019) All outcomes | MD 0.19 [-0.11, 0.50] | 10 studies · 616 participants | GRADE not reported |
Salvadora persica (miswak) mouthrinse vs Chlorhexidine mouthrinse Post-intervention mean plaque score · Medically healthy individuals (adults and children, 6-60 years) · Post-intervention, In vivo clinical trial (human oral cavity), Duration of mouthwash use: <3 weeks For use shorter than 3 weeks chlorhexidine outperformed Salvadora persica for plaque reduction; not GRADE-rated. The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… (2019) All outcomes | MD 0.15 [0.01, 0.29] | 11 studies · 482 participants | GRADE not reported |
Salvadora persica (miswak) mouthrinse vs Chlorhexidine 0.12% mouthrinse Post-intervention mean plaque score · Medically healthy individuals (adults and children, 6-60 years) · Post-intervention, In vivo clinical trial (human oral cavity), Chlorhexidine concentration: 0.12% Salvadora persica was less effective than 0.12% chlorhexidine at reducing plaque (favours chlorhexidine); not GRADE-rated. The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… (2019) All outcomes | MD 0.52 [0.35, 0.69] | 5 studies · 396 participants | GRADE not reported |
Salvadora persica (miswak) mouthrinse vs Chlorhexidine mouthrinse Post-intervention mean plaque score · Medically healthy individuals (adults and children, 6-60 years) · Post-intervention, In vivo clinical trial (human oral cavity), Study quality: high-quality studies In high-quality studies Salvadora persica was less effective than chlorhexidine at reducing plaque (favours chlorhexidine); not GRADE-rated. The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of… (2019) All outcomes | MD 0.19 [0.06, 0.31] | 8 studies · 286 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of chlorhexidine: a systematic… 2019 All outcomes | December 2018 (articles published up to December 2018) | 23 | Critically Low / Critically Low |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Salvadora persica (miswak) mouthrinse vs Chlorhexidine 0.2% mouthrinse · Medically healthy individuals (adults and children, 6-60 years) · 1 review
- Salvadora persica (miswak) mouthrinse vs Pre-treatment (baseline, same group) · Medically healthy individuals (adults and children, 6-60 years) · 1 review
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.