Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

32 questions · 33 findings · 5 reviews

No studies found 9 · 27.3%GRADE not reported 6 · 18.2%Very low 5 · 15.2%Low 6 · 18.2%Moderate 0 · 0%High 7 · 21.2%

Riluzole vs placebo

Short‐term (within 1 month) change in isolated movement, objective and subjective measures of speech production Cooper 2008 reported 3 speech measures: ICARS speech subscale. Scale from: 0 to 8. Higher scores indicate greater clinical severity Syl... · people with speech disorder resulting from hereditary ataxias
1 finding from 1 review

Intervention not reported

Mortality or tracheostomy at 12 months (pooled hazard ratio)(riluzole 100 mg) · patients with ALS/MND

The intervention showed no clear difference in mortality or tracheostomy at 12 months (pooled hazard… (high certainty).

1 finding from 1 review