Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

54 questions · 55 findings · 7 reviews · Anaesthesia

No studies found 18 · 32.7%GRADE not reported 4 · 7.3%Very low 11 · 20%Low 9 · 16.4%Moderate 8 · 14.5%High 5 · 9.1%

Regional anaesthesia vs conventional pain control

Persistent pain 3 to 12 months after breast cancer surgery (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient interview between... · women with breast cancer undergoing elective surgery

Regional anaesthesia may leads to lower persistent pain 3 to 12 months after breast cancer surgery (We… compared with conventional pain control (low certainty).

1 finding from 1 review

Regional anaesthesia vs conventional pain control

Knee Society Score compared to preoperative value · people undergoing total knee replacement
2 findings from 1 review

Infraclavicular block vs all other brachial plexus blocks

Adequate surgical anaesthesia ‐ At 30 minutes post‐block assessment interval · patients with regional anaesthesia of the lower arm

infraclavicular block showed no clear difference in adequate surgical anaesthesia ‐ At 30 minutes post‐block assessment… compared with all other brachial plexus blocks (high certainty).

1 finding from 1 review

Infraclavicular block vs all other brachial plexus blocks

Supplementation required for surgical anaesthesia · patients with regional anaesthesia of the lower arm

infraclavicular block showed no clear difference in supplementation required to achieve adequate surgical anaesthesia compared with all other brachial plexus blocks (high certainty).

1 finding from 1 review

Thoracic epidural anaesthesia vs conventional pain control

Persistent pain 3 to 18 months after thoracotomy (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient interview between 3 to 18 m... · Patients undergoing thoracotomy

Thoracic epidural anaesthesia probably leads to lower persistent pain 3 to 18 months after thoracotomy (We defined… compared with conventional pain control (moderate certainty).

1 finding from 1 review

Intervention not reported

Proportion of maternal participants with desaturation1 · low‐risk term pregnant women undergoing elective caesarean section under regional anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Mean maternal arterial oxygen tension (mm Hg) (PaO2) · low‐risk term pregnant women undergoing elective caesarean section under regional anaesthesia
1 finding from 1 review

Intervention not reported

Mean maternal oxygen saturation (%) · low‐risk term pregnant women undergoing elective caesarean section under regional anaesthesia
1 finding from 1 review

Intervention not reported

Mean oxygen tension (mm Hg) in umbilical artery (UaPO2) · low‐risk term pregnant women undergoing elective caesarean section under regional anaesthesia
1 finding from 1 review

Intervention not reported

Mean oxygen tension (mm Hg) in umbilical vein (UvPO2) · low‐risk term pregnant women undergoing elective caesarean section under regional anaesthesia
1 finding from 1 review