What do systematic reviews say?

Protein supplementation vs control

• Protein supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 101 participants
  Low

Protein supplementation vs control

• Protein supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 68 participants
  Low

Protein supplementation vs control

• Protein supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 68 participants
  Low

Protein supplementation vs control

The review found no eligible studies for this question.

• Protein supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Protein supplementation vs control

• Protein supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Very low

Protein supplementation vs control

It is very uncertain whether protein supplementation changes feeding intolerance compared with control (very low certainty).

• Protein supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
  RR 2.7 [0.13, 58.24]
  1 study · 17 participants
  Very low

Protein supplementation vs control

It is very uncertain whether protein supplementation changes necrotising enterocolitis compared with control (very low certainty).

• Protein supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
  RR 1.11 [0.07, 18.49]
  1 study · 76 participants
  Very low

Balanced protein and energy supplementation vs no intervention or control intervention (control)

Balanced protein and energy supplementation showed no clear difference in neonatal death compared with control or no intervention (low certainty).

• Antenatal dietary education and supplementation to increase energy and protein intake 2015 · Cochrane Headline outcomes only
  RR 0.68 [0.43, 1.07]
  5 studies · 3381 participants
  Low

Balanced protein and energy supplementation vs no intervention or control intervention (control)

Balanced protein and energy supplementation probably leads to lower small‐for‐gestational age compared with control or no intervention (moderate certainty).

• Antenatal dietary education and supplementation to increase energy and protein intake 2015 · Cochrane Headline outcomes only
  RR 0.79 [0.69, 0.9]
  7 studies · 4408 participants
  Moderate

Balanced protein and energy supplementation vs no intervention or control intervention (control)

Balanced protein and energy supplementation showed no clear difference in preterm birth compared with control or no intervention (moderate certainty).

• Antenatal dietary education and supplementation to increase energy and protein intake 2015 · Cochrane Headline outcomes only
  RR 0.96 [0.8, 1.16]
  5 studies · 3384 participants
  Moderate

Balanced protein and energy supplementation vs no intervention or control intervention (control)

• Antenatal dietary education and supplementation to increase energy and protein intake 2015 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 5385 participants
  Moderate

Balanced protein and energy supplementation vs no intervention or control intervention (control)

• Antenatal dietary education and supplementation to increase energy and protein intake 2015 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 2391 participants
  Very low

Balanced protein and energy supplementation vs no intervention or control intervention (control)

• Antenatal dietary education and supplementation to increase energy and protein intake 2015 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Balanced protein and energy supplementation vs no intervention or control intervention (control)

Balanced protein and energy supplementation probably leads to lower stillbirth compared with control or no intervention (moderate certainty).

• Antenatal dietary education and supplementation to increase energy and protein intake 2015 · Cochrane Headline outcomes only
  RR 0.6 [0.39, 0.94]
  5 studies · 3408 participants
  Moderate

Oral protein calorie supplements vs no intervention, placebo or additional nutritional advice compared to placebo

• Oral protein calorie supplementation for children with chronic disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 53 participants
  High

Oral protein calorie supplements vs no intervention, placebo or additional nutritional advice compared to placebo

• Oral protein calorie supplementation for children with chronic disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 125 participants
  Moderate

Oral protein calorie supplements vs no intervention, placebo or additional nutritional advice compared to placebo

• Oral protein calorie supplementation for children with chronic disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 109 participants
  High

Oral protein calorie supplements vs no intervention, placebo or additional nutritional advice compared to placebo

• Oral protein calorie supplementation for children with chronic disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 109 participants
  High

Oral protein calorie supplements vs no intervention, placebo or additional nutritional advice compared to placebo

• Oral protein calorie supplementation for children with chronic disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 109 participants
  High

Oral protein calorie supplements vs no intervention, placebo or additional nutritional advice compared to placebo

• Oral protein calorie supplementation for children with chronic disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 53 participants
  High