Protease‐modulating matrix dressing regimen showed no clear difference in TIme to complete healing compared with any other dressing regimen (low certainty).
It is very uncertain whether protease‐modulating matrix dressing regimen changes proportion of participants healed ‐ short term (4‐8 weeks) compared with any other dressing regimen (very low certainty).
Protease‐modulating matrix dressing regimen showed no clear difference in proportion of participants healed ‐ medium term (12 weeks) compared with any other dressing regimen (low certainty).
Protease‐modulating matrix dressing regimen showed no clear difference in proportion of participants healed ‐ long term (over 24 weeks) compared with any other dressing regimen (low certainty).
Protease‐modulating matrix dressing regimen showed no clear difference in proportion of participants with 1 or more adverse events at 2‐12 weeks compared with any other dressing regimen (low certainty).