Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

32 questions · 36 findings · 2 reviews · Injuries · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 23 · 63.9%Low 11 · 30.6%Moderate 2 · 5.6%High 0 · 0%

FXIII: Prophylactic trials: intervention vs inactive control

Arterial thromboembolic events Post‐operatively · the prevention and treatment of bleeding in patients without haemophilia

FXIII: Prophylactic trials: intervention showed no clear difference in arterial thromboembolic events Up to 5 to 7 weeks post‐operatively compared with inactive control (low certainty).

3 findings from 1 review

FXIII: Prophylactic trials: intervention vs inactive control

Venous thromboembolic events · the prevention and treatment of bleeding in patients without haemophilia

FXIII: Prophylactic trials: intervention showed no clear difference in venous thromboembolic events ‐ Up to 5 to 7 weeks post‐operatively compared with inactive control (low certainty).

2 findings from 1 review

FXIII: Prophylactic trials: intervention vs inactive control

Venous thromboembolic events Up to 30 days post‐operatively · the prevention and treatment of bleeding in patients without haemophilia

FXIII: Prophylactic trials: intervention showed no clear difference in venous thromboembolic events Up to 30 days post‐operatively compared with inactive control (low certainty).

1 finding from 1 review

FIBRINOGEN: Prophylactic trials: intervention vs inactive control

Arterial thrombotic events ‐ up to 30 days post‐operatively · the prevention and treatment of bleeding in patients without haemophilia

FIBRINOGEN: Prophylactic trials: intervention showed no clear difference in arterial thrombotic events Up to 30 days post‐operatively compared with inactive control (low certainty).

2 findings from 1 review

More than 24 hours of antibiotics vs 24 hours of antibiotics

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether more than 24 hours of antibiotics changes abdominal surgical site infection compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐positive and gram‐negative coverage

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes abdominal surgical site infection compared with gram‐positive and gram‐negative coverage (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐positive and gram‐negative coverage

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes intra‐abdominal infection compared with gram‐positive and gram‐negative coverage (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐negative and anaerobic coverage

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes abdominal surgical site infection compared with gram‐negative and anaerobic coverage (very low certainty).

1 finding from 1 review

Anaerobic coverage only vs gram‐negative and anaerobic coverage

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether anaerobic coverage only changes intra‐abdominal infection compared with gram‐negative and anaerobic coverage (very low certainty).

1 finding from 1 review

Gram‐negative and anaerobic coverage vs gram‐positive, gram‐negative, and anaerobic coverage

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether gram‐negative and anaerobic coverage changes abdominal surgical site infection compared with gram‐positive, gram‐negative, and anaerobic coverage (very low certainty).

1 finding from 1 review