Findings

What do systematic reviews say?

402 questions · 411 findings · 41 reviews

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No studies found 99 · 24.1%GRADE not reported 32 · 7.8%Very low 132 · 32.1%Low 112 · 27.3%Moderate 33 · 8%High 3 · 0.7%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Probiotics vs control · Necrotising enterocolitis (before hospital discharge)
  Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2023 · Cochrane Headline outcomes only
  no estimate extracted
  57 studies · 10918 participants
  Low
Direct match · question page
- Probiotics vs control · Necrotising enterocolitis (before hospital discharge)
  Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2023 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 1836 participants
  Low
Direct match · question page
- Probiotics vs placebo · GI function
  Synbiotics, prebiotics and probiotics for solid organ transplant recipients 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
Direct match · question page
- Probiotics vs placebo · Severity of HAEC Â
  Probiotics for the prevention of Hirschsprung‐associated enterocolitis 2022 · Cochrane Headline outcomes only
  OR 0.66 [0.14, 3.16]
  2 studies · 120 participants
  Low
Direct match · question page
- Probiotics vs placebo · Recurrent episodes of HAEC
  Probiotics for the prevention of Hirschsprung‐associated enterocolitis 2022 · Cochrane Headline outcomes only
  OR 0.85 [0.24, 3]
  1 study · 60 participants
  Low

Probiotics vs control

Necrotising enterocolitis · very preterm or very low birth weight infants

1 finding from 1 review

Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2023 · Cochrane Headline outcomes only
no estimate extracted
57 studies · 10918 participants
Low

Probiotics vs control

Mortality before hospital discharge · very preterm or very low birth weight infants

1 finding from 1 review

Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2023 · Cochrane Headline outcomes only
no estimate extracted
54 studies · 10484 participants
Moderate

Probiotics vs control

Late‐onset invasive infection (before hospital discharge) · very preterm or very low birth weight infants

1 finding from 1 review

Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2023 · Cochrane Headline outcomes only
no estimate extracted
49 studies · 9876 participants
Moderate

Probiotics vs control

Neurodevelopmental disability · very preterm or very low birth weight infants

1 finding from 1 review

Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1518 participants
Low

Probiotics vs control

Necrotising enterocolitis · extremely preterm or extremely low birth weight infants

1 finding from 1 review

Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2023 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1836 participants
Low

Probiotics vs control

Mortality before hospital discharge · extremely preterm or extremely low birth weight infants

1 finding from 1 review

Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1723 participants
Low

Probiotics vs control

Late‐onset invasive infection (before hospital discharge) · extremely preterm or extremely low birth weight infants

1 finding from 1 review

Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1533 participants
Low

Probiotics vs control

Neurodevelopmental disability · extremely preterm or extremely low birth weight infants

The review found no eligible studies for this question.

1 finding from 1 review

Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Probiotics vs placebo

Occurrence of HAEC · children with Hirschsprung's disease (HD)

It is very uncertain whether probiotics changes occurrence of HAEC compared with placebo (very low certainty).

1 finding from 1 review

Probiotics for the prevention of Hirschsprung‐associated enterocolitis 2022 · Cochrane Headline outcomes only
OR 0.58 [0.1, 3.43]
2 studies · 120 participants
Very low

Probiotics vs placebo

Serious adverse events · children with Hirschsprung's disease (HD)

1 finding from 1 review

Probiotics for the prevention of Hirschsprung‐associated enterocolitis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
GRADE not reported

Probiotics vs placebo

Severity of HAEC Â · children with Hirschsprung's disease (HD)

Probiotics showed no clear difference in severity of HAEC Â compared with placebo (low certainty).

1 finding from 1 review

Probiotics for the prevention of Hirschsprung‐associated enterocolitis 2022 · Cochrane Headline outcomes only
OR 0.66 [0.14, 3.16]
2 studies · 120 participants
Low

Probiotics vs placebo

Overall mortality · children with Hirschsprung's disease (HD)

1 finding from 1 review

Probiotics for the prevention of Hirschsprung‐associated enterocolitis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
GRADE not reported

Probiotics vs placebo

Withdrawals due to adverse events · children with Hirschsprung's disease (HD)

1 finding from 1 review

Probiotics for the prevention of Hirschsprung‐associated enterocolitis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
GRADE not reported

Probiotics vs placebo

Recurrent episodes of HAEC · children with Hirschsprung's disease (HD)

Probiotics showed no clear difference in recurrent episodes of HAEC compared with placebo (low certainty).

1 finding from 1 review

Probiotics for the prevention of Hirschsprung‐associated enterocolitis 2022 · Cochrane Headline outcomes only
OR 0.85 [0.24, 3]
1 study · 60 participants
Low

Probiotics vs magnesium oxide

Global improvement or treatment success, as defined by primary study · children with chronic constipation without a physical explanation

It is very uncertain whether probiotics changes global improvement/treatment success, as defined by the primary study compared with magnesium oxide (very low certainty).

1 finding from 1 review

Probiotics for treatment of chronic constipation in children 2022 · Cochrane Headline outcomes only
RR 1.08 [0.74, 1.57]
1 study · 36 participants
Very low

Probiotics vs magnesium oxide

Withdrawals due to adverse events · children with chronic constipation without a physical explanation

It is very uncertain whether probiotics changes withdrawals due to adverse events compared with magnesium oxide (very low certainty).

1 finding from 1 review

Probiotics for treatment of chronic constipation in children 2022 · Cochrane Headline outcomes only
RR 0.5 [0.05, 5.04]
2 studies · 77 participants
Very low

Probiotics vs magnesium oxide

Serious adverse events · children with chronic constipation without a physical explanation

1 finding from 1 review

Probiotics for treatment of chronic constipation in children 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 77 participants
GRADE not reported

Probiotics vs magnesium oxide

Frequency of defecation (mean number of bowel movements per week) · children with chronic constipation without a physical explanation

1 finding from 1 review

Probiotics for treatment of chronic constipation in children 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Very low

Probiotics vs placebo

Death · adult patients after liver transplantation.

The review found no eligible studies for this question.

1 finding from 1 review

Synbiotics, prebiotics and probiotics for solid organ transplant recipients 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Probiotics vs placebo

GI function · adult patients after liver transplantation.

The review found no eligible studies for this question.

1 finding from 1 review

Synbiotics, prebiotics and probiotics for solid organ transplant recipients 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found