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Evidence found and GRADE certainty

14 questions · 14 findings · 1 reviews · Musculoskeletal

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No studies found 9 · 64.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 28.6%Moderate 1 · 7.1%High 0 · 0%

Probenecid vs allopurinol

Acute gout attacks · people with chronic gout

Probenecid showed no clear difference in acute gout attacks compared with allopurinol (low certainty).

1 finding from 1 review

Probenecid vs allopurinol

Serum urate normalisation ≤ 5 mg/dL (≤ 0.3 mmol/L) ‐ not measured · people with chronic gout

The review found no eligible studies for this question.

1 finding from 1 review

Benzbromarone vs probenecid

Withdrawals due to adverse events · people with chronic gout

Benzbromarone may leads to lower withdrawal due to adverse events compared with probenecid (low certainty).

1 finding from 1 review

Benzbromarone vs probenecid

Acute gout attacks · people with chronic gout

Benzbromarone showed no clear difference in acute gout attacks compared with probenecid (low certainty).

1 finding from 1 review

Benzbromarone vs probenecid

Serum urate normalisation ≤ 5 mg/dL (≤ 0.3 mmol/L) · people with chronic gout

Benzbromarone probably leads to higher serum urate normalisation ≤ 5 mg/dL (≤ 0.3 mmol/L) compared with probenecid (moderate certainty).

1 finding from 1 review