Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

All cause mortality · Patients with severe malaria

Pre‐referral rectal artesunate probably leads to lower all cause mortality compared with placebo (moderate certainty).

1 finding from 1 review

Pre‐referral rectal artesunate for severe malaria 2014 · Cochrane Headline outcomes only
RR 0.74 [0.59, 0.93]
1 study · 8050 participants
Moderate

Neurodisability · Patients with severe malaria

Pre‐referral rectal artesunate showed no clear difference in neurodisability compared with placebo (low certainty).

1 finding from 1 review

Pre‐referral rectal artesunate for severe malaria 2014 · Cochrane Headline outcomes only
RR 0.68 [0.35, 1.3]
1 study · 17280 participants
Low