Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Heart

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 1 · 14.3%High 1 · 14.3%

All‐cause hospital mortality · participants with ST‐elevation myocardial infarction

Pre‐hospital showed no clear difference in all‐cause hospital mortality compared with in‐hospital thrombolysis (low certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
RR 0.73 [0.37, 1.41]
3 studies · 538 participants
Low

Time to thrombolytic treatment [minutes] · participants with ST‐elevation myocardial infarction

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 438 participants
High

Acute myocardial infarction functional outcomes ‐ ejection fraction [percentage] · participants with ST‐elevation myocardial infarction

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 416 participants
Low

Adverse effects ‐ ventricular Fribrillation · participants with ST‐elevation myocardial infarction

Pre‐hospital showed no clear difference in adverse effects ‐ ventricular Fribrillation compared with in‐hospital thrombolysis (low certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
RR 2.73 [0.68, 10.86]
2 studies · 178 participants
Low

Adverse effects ‐ bleeding complications · participants with ST‐elevation myocardial infarction

Pre‐hospital showed no clear difference in adverse effects ‐ bleeding complications compared with in‐hospital thrombolysis (moderate certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
RR 0.88 [0.41, 1.92]
2 studies · 438 participants
Moderate

Allergic adverse events · participants with ST‐elevation myocardial infarction

Pre‐hospital showed no clear difference in adverse effects ‐ allergic reaction compared with in‐hospital thrombolysis (low certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
RR 0 [0.19, 77.03]
1 study · 100 participants
Low

Adverse effects ‐ Stroke · participants with ST‐elevation myocardial infarction

Pre‐hospital showed no clear difference in adverse effects ‐ Stroke compared with in‐hospital thrombolysis (low certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
RR 2.11 [0.39, 11.4]
1 study · 360 participants
Low