It is very uncertain whether antioxidant(s) changes live birth; antioxidants vs placebo or no treatment/standard… compared with placebo or no treatment/standard treatment (very low certainty).
Antioxidant(s) may leads to higher clinical pregnancy; antioxidants vs placebo or no treatment/standard… compared with placebo or no treatment/standard treatment (low certainty).
Dietary supplements may leads to higher zataria versus placebo Pain relief compared with placebo (low certainty).
It is very uncertain whether dietary supplements changes zinc sulphate versus placebo Adverse effects compared with placebo (very low certainty).
It is very uncertain whether dietary supplements changes ginger versus placebo Adverse effects compared with placebo (very low certainty).
Medical treatment probably leads to higher improvement in pain score at end of treatment: progesterone versus… compared with placebo (moderate certainty).
Medical treatment leads to higher weight gain: progesterone versus placebo compared with placebo (high certainty).
Medical treatment leads to higher bloatedness: progesterone versus placebo compared with placebo (high certainty).
Medical treatment showed no clear difference in improvement in pain score: lofexidine versus placebo compared with placebo (low certainty).
Medical treatment probably leads to higher drowsiness/lethargy: lofexidine versus placebo compared with placebo (moderate certainty).
Medical treatment probably leads to higher dry mouth: lofexidine versus placebo compared with placebo (moderate certainty).
It is very uncertain whether pharmacological intervention changes clinical pregnancyMetformin plus liraglutide vs metformin Met + CC +… compared with pharmacological intervention (very low certainty).
It is very uncertain whether pharmacological intervention changes miscarriageMet + CC + L‐carnitine vs Met + CC + placebo compared with pharmacological intervention (very low certainty).
Oestrogen tablets may leads to higher improvement in symptoms (clinician‐assessed) (oestrogen tablets vs… compared with other regimens (low certainty).
Oestrogen tablets showed no clear difference in adverse events (total adverse events) (oestrogen tablets vs placebo) compared with other regimens (moderate certainty).
Oestrogen cream may leads to higher improvement in symptoms (participant‐assessed) oestrogen cream vs… compared with other regimens (low certainty).
Oestrogen cream may leads to higher improvement in symptoms (clinician‐assessed) (oestrogen cream vs… compared with other regimens (low certainty).
Oestrogen ring showed no clear difference in adverse events (total adverse events) (oestrogen ring vs placebo) compared with other regimens (moderate certainty).