Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

All‐cause mortality maximum · neonates with early‐onset sepsis

It is very uncertain whether piperacillin plus tazobactam changes all‐cause mortality maximum compared with amikacin (very low certainty).

1 finding from 1 review

Antibiotic regimens for early‐onset neonatal sepsis 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.61]
1 study · 59 participants
Very low

Serious adverse events maximum · neonates with early‐onset sepsis

It is very uncertain whether piperacillin plus tazobactam changes serious adverse events maximum compared with amikacin (very low certainty).

1 finding from 1 review

Antibiotic regimens for early‐onset neonatal sepsis 2021 · Cochrane Headline outcomes only
RR 0.97 [0.15, 6.41]
1 study · 59 participants
Very low