What do systematic reviews say?

Phototherapy with LED vs non‐LED light source

Phototherapy with LED showed no clear difference in duration of phototherapy hours compared with non‐LED light source (high certainty).

• Light‐emitting diode phototherapy for unconjugated hyperbilirubinaemia in neonates 2011 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 630 participants
  High

Phototherapy with LED vs non‐LED light source

Phototherapy with LED showed no clear difference in rate of decline of serum total bilirubin mg/dL/hour compared with non‐LED light source (high certainty).

• Light‐emitting diode phototherapy for unconjugated hyperbilirubinaemia in neonates 2011 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 511 participants
  High

Phototherapy vs placebo/no phototherapy

Phototherapy may leads to higher wound healing ‐ proportion of wounds completely healed during compared with placebo/no phototherapy (low certainty).

• Phototherapy for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only
  RR 1.57 [1.08, 2.28]
  4 studies · 116 participants
  Low

Intravenous immunoglobulin plus phototherapy vs phototherapy alone

Intravenous immunoglobulin plus phototherapy showed no clear difference in use of ET (≥ 1); placebo‐controlled studies compared with phototherapy alone (moderate certainty).

• Immunoglobulin for alloimmune hemolytic disease in neonates 2018 · Cochrane Headline outcomes only
  RR 0.98 [0.48, 1.98]
  2 studies · 172 participants
  Moderate

Intravenous immunoglobulin plus phototherapy vs phototherapy alone

• Immunoglobulin for alloimmune hemolytic disease in neonates 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 172 participants
  Moderate