Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 2 reviews

No studies found 7 · 50%GRADE not reported 0 · 0%Very low 3 · 21.4%Low 4 · 28.6%Moderate 0 · 0%High 0 · 0%

Photobiomodulation treatment vs no treatment/sham

Adverse events: AMD progression at 12 months Defined as increased drusen volume or onset of advanced AMD. Conversion to exudative AMD at 12 months Assessed by clinical examination and retinal optical coherence tomography. · people with non‐exudative AMD (AREDS 2 to 4)

Photobiomodulation treatment showed no clear difference in adverse events: AMD progression at 12 months Defined as increased… compared with sham or no treatment (low certainty).

1 finding from 1 review

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Total number of orthodontic appliance adjustment appointments during treatment · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

The review found no eligible studies for this question.

1 finding from 1 review

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Side effects or other adverse events · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

The review found no eligible studies for this question.

1 finding from 1 review

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Duration of orthodontic treatment: alignment stage (mandibular arch) · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether light-emitting diode (LED) photobiomodulation changes duration of orthodontic treatment: alignment stage (mandibular arch) compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Discomfort/pain · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether light-emitting diode (LED) photobiomodulation changes patient perception of pain and discomfort (VAS 0 to 100 mm) compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Orthodontic tooth movement (OTM) during alignment stage · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

The review found no eligible studies for this question.

1 finding from 1 review

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Patient-reported need for analgesics · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

The review found no eligible studies for this question.

1 finding from 1 review

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Rate of orthodontic tooth movement during space closure stage (maxillary canine distalisation), mm/day · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether light-emitting diode (LED) photobiomodulation changes rate of orthodontic tooth movement during space closure stage… compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review