Cephalosporins showed no clear difference in resolution of symptoms post‐treatment (ITT analysis) compared with penicillin (low certainty).
Carbacephem may leads to lower resolution of symptoms post‐treatment (ITT analysis) compared with penicillin (low certainty).
Carbacephem showed no clear difference in resolution of symptoms post‐treatment (evaluable participants) compared with penicillin (low certainty).
Carbacephem showed no clear difference in incidence of relapse (evaluable participants) compared with penicillin (low certainty).
Carbacephem showed no clear difference in adverse events (ITT analysis) compared with penicillin (low certainty).
It is very uncertain whether cephalosporins changes resolution of symptoms post‐treatment (evaluable participants) compared with penicillin (very low certainty).
Cephalosporins may leads to lower incidence of relapse (evaluable participants) compared with penicillin (low certainty).
It is very uncertain whether cephalosporins changes adverse events (ITT analysis) compared with penicillin (very low certainty).
Macrolides showed no clear difference in resolution of symptoms post‐treatment (ITT analysis) compared with penicillin (low certainty).
Macrolides showed no clear difference in resolution of symptoms post‐treatment (evaluable participants) compared with penicillin (low certainty).
Macrolides showed no clear difference in incidence of relapse (evaluable participants) compared with penicillin (low certainty).
Macrolides showed no clear difference in adverse events (ITT analysis) compared with penicillin (low certainty).