Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

197 questions · 197 findings · 34 reviews · Cystic Fibrosis and Genetic Disorders · Headline outcomes only

No studies found 83 · 42.1%GRADE not reported 0 · 0%Very low 41 · 20.8%Low 38 · 19.3%Moderate 31 · 15.7%High 4 · 2%

Zinc vs placebo

Pulmonary exacerbations number of participants requiring IV antibiotics · children with cystic fibrosis

Summary of findings: Zinc supplementation showed no clear difference in pulmonary exacerbations number of participants requiring IV… compared with placebo (moderate certainty).

1 finding from 1 review