Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Multiple Sclerosis and Rare Diseases of the CNS

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No studies found 1 · 20%GRADE not reported 0 · 0%Very low 2 · 40%Low 2 · 40%Moderate 0 · 0%High 0 · 0%

PUFA vs monounsaturated fatty acid (MUFA)

Relapse · people with multiple sclerosis

It is very uncertain whether polyunsaturated fatty acid (PUFA) changes relapse(assessed as number of participants experiencing relapse) compared with monounsaturated fatty acid (MUFA) (very low certainty).

1 finding from 1 review

Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes only
RR 1.02 [0.88, 1.2]
3 studies · 217 participants
Very low

PUFA vs monounsaturated fatty acid (MUFA)

Change in validated disability scale ( · people with multiple sclerosis

1 finding from 1 review

Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 102 participants
Very low

PUFA vs monounsaturated fatty acid (MUFA)

Global impression of deterioration (investigator defined global impression of deterioration) · people with multiple sclerosis

Polyunsaturated fatty acid (PUFA) showed no clear difference in global impression of deterioration (investigator defined global… compared with monounsaturated fatty acid (MUFA) (low certainty).

1 finding from 1 review

Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes only
RR 0.85 [0.71, 1.03]
4 studies · 542 participants
Low

PUFA vs monounsaturated fatty acid (MUFA)

MRI activity ‐ not measured · people with multiple sclerosis

The review found no eligible studies for this question.

1 finding from 1 review

Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PUFA vs monounsaturated fatty acid (MUFA)

SAEs · people with multiple sclerosis

1 finding from 1 review

Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low