What do systematic reviews say?

PAP therapy vs usual care

It is very uncertain whether PAP therapy changes all‐cause mortality compared with usual care (very low certainty).

• Positive airway pressure therapy for the treatment of central sleep apnoea associated with heart failure 2019 · Cochrane Headline outcomes only
  RR 0.81 [0.54, 1.21]
  6 studies · 1804 participants
  Very low

PAP therapy vs usual care

PAP therapy showed no clear difference in cardiac‐related mortality compared with usual care (moderate certainty).

• Positive airway pressure therapy for the treatment of central sleep apnoea associated with heart failure 2019 · Cochrane Headline outcomes only
  RR 0.97 [0.77, 1.24]
  5 studies · 1775 participants
  Moderate

PAP therapy vs usual care

PAP therapy showed no clear difference in all‐cause rehospitalisation compared with usual care (low certainty).

• Positive airway pressure therapy for the treatment of central sleep apnoea associated with heart failure 2019 · Cochrane Headline outcomes only
  RR 0.95 [0.7, 1.3]
  5 studies · 1533 participants
  Low

PAP therapy vs usual care

PAP therapy showed no clear difference in cardiac‐related rehospitalisation compared with usual care (low certainty).

• Positive airway pressure therapy for the treatment of central sleep apnoea associated with heart failure 2019 · Cochrane Headline outcomes only
  RR 0.97 [0.7, 1.35]
  5 studies · 1533 participants
  Low

PAP therapy vs usual care

• Positive airway pressure therapy for the treatment of central sleep apnoea associated with heart failure 2019 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 1617 participants
  Low
• Positive airway pressure therapy for the treatment of central sleep apnoea associated with heart failure 2019 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1458 participants
  Low

PAP therapy vs usual care

• Positive airway pressure therapy for the treatment of central sleep apnoea associated with heart failure 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1412 participants
  Low

Papilla base incision (PBI) vs Complete papilla mobilisation (sulcular incision)

It is very uncertain whether papilla base incision (PBI) changes height loss of interdental papilla - 1 year compared with complete papilla mobilisation (sulcular incision) (very low certainty).

• Endodontic procedures for retreatment of periapical lesions 2016 · Cochrane All outcomes

  1 year
  MD -1.04 [-1.48, -0.60]
  1 study · 12 participants
  Very low

Myofunctional therapy vs CPAP + Myofunctional therapy

• Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 49 participants
  Low

Myofunctional therapy vs CPAP + Myofunctional therapy

• Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 49 participants
  Low

Myofunctional therapy vs CPAP + Myofunctional therapy

• Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 49 participants
  Low

Myofunctional therapy vs CPAP + Myofunctional therapy

• Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 49 participants
  Low

Positional therapy vs continuous positive airway pressure (CPAP)

• Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Low

Positional therapy vs continuous positive airway pressure (CPAP)

• Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 33 participants
  Low

Positional therapy vs continuous positive airway pressure (CPAP)

• Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Moderate

Positional therapy vs continuous positive airway pressure (CPAP)

• Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  GRADE not reported

Positional therapy vs continuous positive airway pressure (CPAP)

• Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Low

Positional therapy vs continuous positive airway pressure (CPAP)

• Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Low

Positional therapy vs continuous positive airway pressure (CPAP)

• Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  GRADE not reported

Myofunctional therapy vs continuous positive airway pressure (CPAP)

• Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 54 participants
  Low

Myofunctional therapy vs continuous positive airway pressure (CPAP)

• Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 54 participants
  Low