All‐cause mortality · cognitively healthy people in late life
Other NSAIDs showed no clear difference in mortality compared with placebo (moderate certainty).
1 finding from 1 review
Incidence of mild cognitive impairment · cognitively healthy people in late life
Other NSAIDs showed no clear difference in incidence of mild cognitive impairment compared with placebo (low certainty).
1 finding from 1 review
Activities of daily living · cognitively healthy people in late life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · cognitively healthy people in late life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Incidence of Alzheimer's disease · cognitively healthy people in late life
Other NSAIDs showed no clear difference in incidence of Alzheimer's disease compared with placebo (moderate certainty).
1 finding from 1 review
Adverse events: myocardial infarction · cognitively healthy people in late life
Other NSAIDs showed no clear difference in adverse events –myocardial infarction compared with placebo (moderate certainty).
1 finding from 1 review
Adverse effects ‐ Stroke · cognitively healthy people in late life
Other NSAIDs showed no clear difference in adverse events – stroke compared with placebo (moderate certainty).
1 finding from 1 review
Other side effects of NSAID use · women undergoing breast surgery
It is very uncertain whether NSAID changes other side effects of NSAID use compared with other analgesic (very low certainty).
1 finding from 1 review
Incidence of dementia · older people with age‐related memory loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Gastrointestinal adverse events · older people with age‐related memory loss
NSAIDs (celecoxib) may leads to higher adverse events – gastrointestinal compared with placebo (low certainty).
1 finding from 1 review
All‐cause mortality · older people with age‐related memory loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cognitive decline · older people with age‐related memory loss
1 finding from 1 review
Activities of daily living · older people with age‐related memory loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · older people with age‐related memory loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Other side effects of NSAID use · women undergoing breast surgery
NSAID showed no clear difference in other side effects of NSAID use compared with placebo (low certainty).
1 finding from 1 review
Number of patients with postoperative nausea and vomiting (24 hours postoperatively) · women undergoing breast surgery
NSAID probably leads to lower incidence rate or severity of postoperative nausea, vomiting, or both compared with other analgesic (moderate certainty).
1 finding from 1 review
Bleeding from any location within 90 days · women undergoing breast surgery
It is very uncertain whether NSAID changes bleeding from any location within 90 days compared with other analgesic (very low certainty).
1 finding from 1 review
Opioid use within 24 (± 12) hours of surgery · women undergoing breast surgery
1 finding from 1 review
Incidence of breast hematoma · women undergoing breast surgery
It is very uncertain whether NSAID changes incidence of breast hematoma within 90 days of breast surgery compared with other analgesic (very low certainty).
1 finding from 1 review
Pain intensity 24 (± 12) hours following surgery · women undergoing breast surgery
1 finding from 1 review