Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

77 questions · 88 findings · 11 reviews · Headline outcomes only

No studies found 18 · 20.5%GRADE not reported 0 · 0%Very low 26 · 29.5%Low 30 · 34.1%Moderate 14 · 15.9%High 0 · 0%

Neuromuscular electrical stimulation + other intervention (e.g. exercise) vs other intervention alone

Kujala patellofemoral disorders score Scale from: 0 to 100 (higher scores = better function) · patients with patellofemoral pain syndrome (symptoms > 4 weeks (1 study); symptoms > 6 weeks (1 study); symptoms > 8 weeks (1 study); not…
1 finding from 1 review

Oral misoprostol one‐ to two‐hourly vs oral misoprostol four‐ to six‐hourly

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour with intact membranes

It is very uncertain whether oral misoprostol one‐ to two‐hourly changes uterine hyperstimulation without fetal heart rate changes compared with oral misoprostol four‐ to six‐hourly (very low certainty).

1 finding from 1 review

Oral misoprostol 20 µg hourly titrated vs oral misoprostol 25 µg two‐hourly static

Uterine hyperstimulation with fetal heart rate changes · induction of labour.

It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation with FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).

1 finding from 1 review

Oral misoprostol 20 µg hourly titrated vs oral misoprostol 25 µg two‐hourly static

Uterine hyperstimulation without fetal heart rate changes · induction of labour.

It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation without FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).

1 finding from 1 review

Oral misoprostol vs vaginal dinoprostone

Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol may leads to lower uterine hyperstimulation with fetal heart rate changes compared with vaginal dinoprostone (low certainty).

1 finding from 1 review

Oral misoprostol vs vaginal dinoprostone

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol probably leads to lower uterine hyperstimulation without fetal heart rate changes compared with vaginal dinoprostone (moderate certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol may leads to lower uterine hyperstimulation with fetal heart rate changes compared with vaginal misoprostol (low certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol may leads to lower uterine hyperstimulation without fetal heart rate changes compared with vaginal misoprostol (low certainty).

1 finding from 1 review

Oral misoprostol vs intravenous (IV) oxytocin

Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes uterine hyperstimulation with fetal heart rate changes compared with intravenous oxytocin (very low certainty).

1 finding from 1 review

Oral misoprostol vs intravenous (IV) oxytocin

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes uterine hyperstimulation without fetal heart rate changes compared with intravenous oxytocin (very low certainty).

1 finding from 1 review

Oral misoprostol vs placebo/no treatment

Uterine hyperstimulation with fetal heart rate changes · women with ruptured membranes in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes uterine hyperstimulation with fetal heart rate changes compared with placebo/no treatment (very low certainty).

1 finding from 1 review