Oral vs IV followed by oral (11 days) therapy
Fever clearance time · children with acute pyelonephritis
1 finding from 1 review
- no estimate extracted2 studies · 808 participantsModerate
Findings
What do systematic reviews say?
6 questions · 6 findings · 2 reviews · Kidney and Transplant · Headline outcomes only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 3 · 50%High 0 · 0%
Oral vs IV followed by oral (11 days) therapy
Renal parenchymal damage at 6 to 12 months: all included children with acute pyelonephritis DMSA scans · children with acute pyelonephritis
Oral showed no clear difference in renal parenchymal damage at 6 to 12 months: all included children… compared with IV followed by oral (11 days) therapy (moderate certainty).
1 finding from 1 review
- RR 0.82 [0.59, 1.12]4 studies · 943 participantsModerate
Oral vs IV followed by oral (11 days) therapy
Renal parenchymal damage at 6 to 12 months: children with renal parenchymal damage on initial DMSA · children with acute pyelonephritis
Oral showed no clear difference in renal parenchymal damage at 6 to 12 months: children with renal… compared with IV followed by oral (11 days) therapy (moderate certainty).
1 finding from 1 review
- RR 0.79 [0.61, 1.03]4 studies · 681 participantsModerate
Oral or topical or intraperitoneal antibiotics vs placebo/no treatment
Peritonitis · chronic peritoneal dialysis patients
Oral or topical or intraperitoneal antibiotics showed no clear difference in peritonitis (number of patients with one or more episodes) compared with placebo/no treatment (low certainty).
1 finding from 1 review
- Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes onlyRR 0.82 [0.57, 1.19]5 studies · 395 participantsLow
Oral or topical or intraperitoneal antibiotics vs placebo/no treatment
Exit‐site/tunnel infection · chronic peritoneal dialysis patients
Oral or topical or intraperitoneal antibiotics showed no clear difference in exit‐site/tunnel infection (number of patients with one or more… compared with placebo/no treatment (low certainty).
1 finding from 1 review
- Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes onlyRR 0.45 [0.19, 1.04]3 studies · 191 participantsLow
Oral or topical or intraperitoneal antibiotics vs placebo/no treatment
Catheter removal or replacement · chronic peritoneal dialysis patients
Oral or topical or intraperitoneal antibiotics showed no clear difference in catheter removal or replacement (number of patients) compared with placebo/no treatment (low certainty).
1 finding from 1 review
- Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes onlyRR 0.82 [0.46, 1.46]5 studies · 395 participantsLow