Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

85 questions · 86 findings · 7 reviews

No studies found 29 · 33.7%GRADE not reported 4 · 4.7%Very low 19 · 22.1%Low 26 · 30.2%Moderate 8 · 9.3%High 0 · 0%

Opioid antagonists vs placebo

Nausea · preventing nausea and vomiting
2 findings from 1 review

Opioid antagonists vs placebo

Treatment responseaClinical Global Impressions ‐ Improvement Scale (CGI‐I) (no. of responders) & NIMH Trichotillomania Severity Scale (NIMH‐TSS) (no. of responders as > 50% reduction) · adults with trichotillomania

It is very uncertain whether opioid antagonists changes treatment responseaClinical Global Impressions ‐ Improvement Scale… compared with placebo (very low certainty).

1 finding from 1 review