What do systematic reviews say?

Visual screening (oral visual inspection) by trained health workers vs No screening

Visual screening (oral visual inspection) by trained health workers led to lower stage at diagnosis (early-stage detection) compared with no screening; GRADE not reported.

• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up
  RR 0.81 [0.70, 0.93]
  1 study · 523 participants
  GRADE not reported
• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up · High-risk individuals (tobacco and/or alcohol users)
  RR 0.82 [0.71, 0.95]
  1 study · 486 participants
  GRADE not reported

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

The review found no eligible studies for this question.

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
  No data were available for this patient-reported outcome in the single included trial.
  0 studies
  No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

The review found no eligible studies for this question.

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
  Nasalance score by nasometry and pressure-flow measure: the single included trial (Ysunza 2001) provided no data for this outcome.
  0 studies
  No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

The review found no eligible studies for this question.

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
  No data were available for this patient-reported outcome in the single included trial.
  0 studies
  No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes

  3 months post-operatively
  Complete closure occurred in 32 (86%) of the participants in group 1 (MIPP) and in 31 (89%) in group 2, P > 0.05. After eliminating the nine patients with residual velopharyngeal insufficiency, the post-operative gap…
  1 study · 72 participants
  GRADE not reported

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
  There were no reports of failure of muscle fusion after surgery.
  1 study · 72 participants
  GRADE not reported

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

The review found no eligible studies for this question.

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
  The trial report provided no information on this adverse event; no information on adverse events or serious complications was reported.
  0 studies
  No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
  The investigators stated that none of the participants reported obstructive sleep apnoea after the interventions.
  1 study · 72 participants
  GRADE not reported

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes

  3 months post-operatively
  Five (14%) of the participants in group 1 (MIPP) and four (11%) in group 2 had residual post-operative velopharyngeal insufficiency, P > 0.05. The report provided no details on post-operative speech assessment other…
  1 study · 72 participants
  GRADE not reported

Visual screening (oral visual inspection) by trained health workers vs No screening

Visual screening (oral visual inspection) by trained health workers showed no clear difference in oral cancer mortality (disease-specific) compared with no screening (low certainty).

• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up
  RR 0.88 [0.69, 1.12]
  1 study · 191873 participants
  Low
• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up · High-risk individuals (tobacco and/or alcohol users)
  RR 0.76 [0.60, 0.97]
  1 study
  GRADE not reported

Visual screening (oral visual inspection) by trained health workers vs No screening

• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  9 years (three cycles)
  The costs associated with the screening programme were reported after three cycles (nine years) (Subramanian 2009) (Additional Table 8). The benefit produced by a screen was 269.31 life-years saved per 100,000 for all…
  1 study
  GRADE not reported

Visual screening (oral visual inspection) by trained health workers vs No screening

The review found no eligible studies for this question.

• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up
  No harms were reported.
  0 studies
  No studies found

Visual screening (oral visual inspection) by trained health workers vs No screening

Visual screening (oral visual inspection) by trained health workers showed no clear difference in oral cancer incidence compared with no screening; GRADE not reported.

• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up
  RR 1.14 [0.91, 1.44]
  1 study · 191873 participants
  GRADE not reported
• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up · High-risk individuals (tobacco and/or alcohol users)
  RR 0.97 [0.79, 1.19]
  1 study
  GRADE not reported

Visual screening (oral visual inspection) by trained health workers vs No screening

The review found no eligible studies for this question.

• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up
  Data on quality of life were not reported.
  0 studies
  No studies found

Visual screening (oral visual inspection) by trained health workers vs No screening

• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  15-year follow-up
  Across the four cycles (15 years), the reported sensitivity of the visual examination in detecting oral cancer was 67.4% (188/279). No information on the specificity or the positive predictive value of the programme…
  1 study
  GRADE not reported

Visual screening (oral visual inspection) by trained health workers vs No screening

• Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes

  5-year survival
  A significantly higher five-year survival rate was reported in the screened group (55.5%) compared to the control (43.4%) (P value = 0.003).
  1 study · 523 participants
  GRADE not reported