All‐cause mortality · people aged 65 years and older living with frailty
Case management for integrated care showed no clear difference in mortality compared with usual care of older people living with frailty (low certainty).
1 finding from 1 review
Change in place of residence to a nursing or residential home · people aged 65 years and older living with frailty
Case management for integrated care showed no clear difference in change in place of residence to a nursing or residential home compared with usual care of older people living with frailty (low certainty).
1 finding from 1 review
Quality of life · people aged 65 years and older living with frailty
1 finding from 1 review
Serious adverse effects · people aged 65 years and older living with frailty
1 finding from 1 review
Physical function · people aged 65 years and older living with frailty
1 finding from 1 review
Change in healthcare utilisation (hospital admissions) · people aged 65 years and older living with frailty
Case management for integrated care showed no clear difference in change in healthcare utilisation (hospital admissions) compared with usual care of older people living with frailty (moderate certainty).
1 finding from 1 review
Change in costs · people aged 65 years and older living with frailty
1 finding from 1 review
Death from any cause · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
It is very uncertain whether long‐stored ('older') PRBC (≥ 21 days of storage) changes death from any cause compared with short‐stored (fresh) PRBC (< 21 days of storage) (very low certainty).
1 finding from 1 review
Transfusion‐related acute lung injury ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Postoperative infections ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Post‐injury coagulopathy ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Multiple organ failure post‐injury ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse event (Hyperkalaemia) ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse event (Metabolic acidosis) · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
1 finding from 1 review
Patient Activation Measure (PAM) · older patients with multi‐morbidity
1 finding from 1 review
Patient enablement and engagement (b) Morisky Medication Adherence Scale at 15 months after baseline (8‐item yes‐no survey. Range of scores from 0 to 8. Lower scores suggest non‐adherence) (Morisky 2008) · older patients with multi‐morbidity
1 finding from 1 review
Participants with adverse events: 1 or more serious adverse events regardless of type of storage of the vaccine Clinical or laboratory criteria · healthy older adults aged ≥ 60 years
Live zoster vaccine showed no clear difference in participants with adverse events: 1 or more serious adverse events… compared with placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
Frequency of skin damage (as recorded by clinicians according to STAR Skin Tear Classification) Outcome measured during 6 months · people 60 years of age and older
1 finding from 1 review
Intervention not reported
Transepidermal water loss (TEWL) Measured using temperature‐adjusted g/m²/h with the Tewameter TM 300 (Courage + Khazaka, Cologne, Germany) Hahnel 2017: measured at 56 ± 4 days Shishido 2017: measured 15 minutes after wiping the skin with a dry to... · people 60 years of age and older
1 finding from 1 review
Home visit with encouragement to receive influenza vaccination compared to home visit with safety intervention · people aged 60 years and older living in the community
Enhancing vaccination access showed no clear difference in home visit with encouragement to receive influenza vaccination… compared with no intervention or another intervention (high certainty).
1 finding from 1 review