What do systematic reviews say?

Nitrofurantoin and close surveillance vs close surveillance alone

It is very uncertain whether nitrofurantoin and close surveillance changes recurrent pyelonephritis compared with close surveillance alone (very low certainty).

• Interventions for preventing recurrent urinary tract infection during pregnancy 2015 · Cochrane Headline outcomes only
  RR 0.89 [0.31, 2.53]
  1 study · 167 participants
  Very low

Nitrofurantoin and close surveillance vs close surveillance alone

It is very uncertain whether nitrofurantoin and close surveillance changes recurrent UTI (cystitis) compared with close surveillance alone (very low certainty).

• Interventions for preventing recurrent urinary tract infection during pregnancy 2015 · Cochrane Headline outcomes only
  RR 0.3 [0.06, 1.38]
  1 study · 167 participants
  Very low

Nitrofurantoin and close surveillance vs close surveillance alone

It is very uncertain whether nitrofurantoin and close surveillance changes preterm birth (< 37 weeks) compared with close surveillance alone (very low certainty).

• Interventions for preventing recurrent urinary tract infection during pregnancy 2015 · Cochrane Headline outcomes only
  RR 1.18 [0.42, 3.35]
  1 study · 147 participants
  Very low

Nitrofurantoin and close surveillance vs close surveillance alone

It is very uncertain whether nitrofurantoin and close surveillance changes birthweight < 2500 (g) compared with close surveillance alone (very low certainty).

• Interventions for preventing recurrent urinary tract infection during pregnancy 2015 · Cochrane Headline outcomes only
  RR 2.03 [0.53, 7.8]
  1 study · 147 participants
  Very low

Nitrofurantoin and close surveillance vs close surveillance alone

• Interventions for preventing recurrent urinary tract infection during pregnancy 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 147 participants
  Very low

Nitrofurantoin and close surveillance vs close surveillance alone

It is very uncertain whether nitrofurantoin and close surveillance changes five‐minute Apgar score < seven compared with close surveillance alone (very low certainty).

• Interventions for preventing recurrent urinary tract infection during pregnancy 2015 · Cochrane Headline outcomes only
  RR 2.03 [0.19, 21.87]
  1 study · 147 participants
  Very low

Nitrofurantoin and close surveillance vs close surveillance alone

It is very uncertain whether nitrofurantoin and close surveillance changes miscarriages compared with close surveillance alone (very low certainty).

• Interventions for preventing recurrent urinary tract infection during pregnancy 2015 · Cochrane Headline outcomes only
  RR 3.11 [0.33, 29.29]
  1 study · 167 participants
  Very low