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What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 1 reviews · Eyes and Vision

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No studies found 5 · 62.5%GRADE not reported 0 · 0%Very low 3 · 37.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Neuroprotection vs control

Progression of visual field loss (worsening of one or more stages, accordingto the Glaucoma Staging System‐2) (at 12 months) · people with open‐angle glaucoma

It is very uncertain whether neuroprotection changes visual field: the proportion of participants with progression of… compared with control (very low certainty).

1 finding from 1 review

Neuroprotection vs control

Vertical cup‐disc ratio: the proportion of participants with asymmetrical vertical cup‐disc ratio greater than 0.3 at 4 years' · people with open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Neuroprotection vs control

Adverse effects: ocular allergy to the study medication requiring discontinuation up to 4 years' · people with open‐angle glaucoma

It is very uncertain whether neuroprotection changes adverse effects: ocular allergy to the study medication requiring… compared with control (very low certainty).

1 finding from 1 review