Findings

What do systematic reviews say?

4 questions · 6 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 16.7%Low 0 · 0%Moderate 2 · 33.3%High 3 · 50%

Incidence of dementia · Older people living in the community

Multi‐domain interventions showed no clear difference in incidence of dementia compared with usual care/placebo (high certainty).

1 finding from 1 review

Multi‐domain interventions for the prevention of dementia and cognitive decline 2021 · Cochrane Headline outcomes only
RR 0.94 [0.76, 1.18]
2 studies · 7256 participants
High

Incidence of MCI · Older people living in the community

Multi‐domain interventions showed no clear difference in incidence of MCI compared with usual care/placebo (moderate certainty).

1 finding from 1 review

Multi‐domain interventions for the prevention of dementia and cognitive decline 2021 · Cochrane Headline outcomes only
RR 0.97 [0.76, 1.23]
1 study · 3802 participants
Moderate

Cognitive decline · Older people living in the community

3 findings from 1 review

Multi‐domain interventions for the prevention of dementia and cognitive decline 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 4617 participants
High
Multi‐domain interventions for the prevention of dementia and cognitive decline 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 8697 participants
Moderate
Multi‐domain interventions for the prevention of dementia and cognitive decline 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1554 participants
Very low

All‐cause mortality · Older people living in the community

Multi‐domain interventions showed no clear difference in mortality compared with usual care/placebo (high certainty).

1 finding from 1 review

Multi‐domain interventions for the prevention of dementia and cognitive decline 2021 · Cochrane Headline outcomes only
RR 0.93 [0.84, 1.04]
4 studies · 11487 participants
High