Vaginal surgery with mesh may leads to higher mesh exposure compared with without mesh (low certainty).
Transvaginal permanent mesh probably leads to higher mesh exposure compared with native tissue repair (moderate certainty).
Vaginal POP surgery with armed mesh may leads to higher one type of POP surgery vs another: armed anterior mesh vs anterior… compared with anterior native tissue repair (low certainty).
Vaginal surgery with mesh showed no clear difference in awareness of prolapse compared with without mesh (moderate certainty).
Vaginal surgery with mesh showed no clear difference in surgery for recurrent prolapse compared with without mesh (moderate certainty).
Vaginal surgery with mesh showed no clear difference in prolapse on examination (Stage 2 or above) ‐ Any recurrent prolapse compared with without mesh (low certainty).
Vaginal surgery with mesh showed no clear difference in bladder injury compared with without mesh (low certainty).
Vaginal surgery with mesh showed no clear difference in bladder function ‐ Stress incontinence compared with without mesh (moderate certainty).
Transvaginal permanent mesh probably leads to lower awareness of prolapse (0.5 to 7 years) compared with native tissue repair (moderate certainty).
Transvaginal permanent mesh may leads to higher repeat surgery (0.5 to 7 years) compared with native tissue repair (low certainty).
It is very uncertain whether transvaginal permanent mesh changes recurrent prolapse on examination (any compartment) compared with native tissue repair (very low certainty).
Transvaginal permanent mesh may leads to higher visceral injury compared with native tissue repair (low certainty).
Transvaginal permanent mesh probably leads to higher bladder function compared with native tissue repair (moderate certainty).
Transvaginal permanent mesh showed no clear difference in painful intercourse ‐ de novo dyspareunia compared with native tissue repair (moderate certainty).
It is very uncertain whether transvaginal permanent mesh changes quality of life compared with native tissue repair (very low certainty).
Anterior prolapse repair: native tissue probably leads to lower repeat surgery for prolapse, SUI or mesh exposure (1‐3 years) compared with polypropylene mesh (moderate certainty).
It is very uncertain whether vaginal hysterectomy changes mesh exposure compared with sacral hysteropexy/cervicopexy (uterine prolapse) (very low certainty).
It is very uncertain whether vaginal hysteropexy changes mesh exposure (1‐4 years) compared with sacral hysteropexy (uterine prolapse) (very low certainty).
Absorbable showed no clear difference in suture/mesh exposure compared with non absorbable sutures (low certainty).