Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Drugs and Alcohol

No studies found 0 · 0%GRADE not reported 2 · 50%Very low 2 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

It is very uncertain whether melatonin changes benzodiazepine discontinuation, end of intervention compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
RR 1.2 [0.73, 1.96]
4 studies · 219 participants
Very low

Benzodiazepine discontinuation, longest · adults who withdraw from chronic benzodiazepine use

It is very uncertain whether melatonin changes benzodiazepine discontinuation, longest compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
RR 1.03 [0.47, 2.27]
1 study · 38 participants
Very low

Benzodiazepine withdrawal symptoms, end of intervention · adults who withdraw from chronic benzodiazepine use

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Benzodiazepine withdrawal symptoms, longest · adults who withdraw from chronic benzodiazepine use

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported