Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 6 reviews · Injuries · Headline outcomes only

No studies found 4 · 28.6%GRADE not reported 0 · 0%Very low 1 · 7.1%Low 3 · 21.4%Moderate 3 · 21.4%High 3 · 21.4%

Helicopter emergency medical services vs ground emergency medical services

Overall unadjusted mortality · adults (age > 15 years) with major trauma (ISS > 15)

It is very uncertain whether helicopter emergency medical services changes overall unadjusted mortality compared with ground emergency medical services (very low certainty).

1 finding from 1 review

School injury prevention programmes vs controls

Self‐reported medically or non‐medically attended unintentional injuries or injuries with an unspecified intent (injury rates adjusted for clustering) · children and young people aged 0 to 18 years

School injury prevention programmes showed no clear difference in self‐reported medically or non‐medically attended unintentional… compared with controls (low certainty).

1 finding from 1 review

Intervention not reported

Self‐reported injuries or medically‐attended injuries · cyclists

The review found no eligible studies for this question.

1 finding from 1 review

Parenting interventions vs usual care

Medically attended or self‐reported injuries ‐ RCTs only · parents of children between the ages of 0 and 18 years

Parenting interventions probably leads to lower medically attended or self‐reported injuries ‐ RCTs only compared with usual care (moderate certainty).

1 finding from 1 review

Intervention not reported

Greatest crash reductions in areas within 2km of camera sites, with 31% (1100), 39% (2200), 19% (500) and 21% (1600) reductions estimated for hospitalisation, medically treated, other injury and non‐injury crashes respectively.
1 finding from 1 review

Decompressive craniectomy vs medical treatment

Mortality at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy probably leads to lower mortality at 6 months compared with medical treatment only (moderate certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

Mortality at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy leads to lower mortality at 12 months compared with medical treatment only (high certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

'Unfavorable outcome' as per original Cochrane protocol at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy may leads to higher 'Unfavorable outcome' as per original Cochrane protocol at 6 months compared with medical treatment only (low certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy showed no clear difference in 'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months compared with medical treatment only (high certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

Changes in ICP from randomization up to 48 h · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy showed no clear difference in changes in ICP from randomization up to 48 h compared with medical treatment only (moderate certainty).

1 finding from 1 review