What do systematic reviews say?

Pressure support vs T‐tube

Pressure support showed no clear difference in weaning success compared with T‐tube (low certainty).

• Pressure support versus T‐tube for weaning from mechanical ventilation in adults 2014 · Cochrane Headline outcomes only
  RR 1.07 [0.97, 1.17]
  9 studies · 935 participants
  Low

Pressure support vs T‐tube

Pressure support showed no clear difference in ICU mortality compared with T‐tube (low certainty).

• Pressure support versus T‐tube for weaning from mechanical ventilation in adults 2014 · Cochrane Headline outcomes only
  RR 0.81 [0.53, 1.23]
  5 studies · 725 participants
  Low

Pressure support vs T‐tube

Pressure support showed no clear difference in reintubation compared with T‐tube (low certainty).

• Pressure support versus T‐tube for weaning from mechanical ventilation in adults 2014 · Cochrane Headline outcomes only
  RR 0.92 [0.66, 1.26]
  7 studies · 823 participants
  Low

Pressure support vs T‐tube

• Pressure support versus T‐tube for weaning from mechanical ventilation in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 118 participants
  Low

Pressure support vs T‐tube

It is very uncertain whether pressure support changes pneumonia compared with T‐tube (very low certainty).

• Pressure support versus T‐tube for weaning from mechanical ventilation in adults 2014 · Cochrane Headline outcomes only
  RR 0.67 [0.08, 5.85]
  2 studies · 118 participants
  Very low

Pressure support vs T‐tube

Pressure support probably leads to higher successful spontaneous breathing trial compared with T‐tube (moderate certainty).

• Pressure support versus T‐tube for weaning from mechanical ventilation in adults 2014 · Cochrane Headline outcomes only
  RR 1.09 [1.02, 1.17]
  4 studies · 940 participants
  Moderate

Pressure‐controlled ventilation vs volume‐controlled ventilation

• Pressure‐controlled versus volume‐controlled ventilation for acute respiratory failure due to acute lung injury (ALI)… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 983 participants
  GRADE not reported

Music vs usual care

• Music interventions for mechanically ventilated patients 2014 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 269 participants
  Very low

Music vs usual care

• Music interventions for mechanically ventilated patients 2014 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 269 participants
  Very low

Music vs usual care

• Music interventions for mechanically ventilated patients 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 98 participants
  Very low

High levels of PEEP vs low levels of PEEP

High levels of PEEP showed no clear difference in mortality before hospital discharge compared with low levels of PEEP (moderate certainty).

• High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes only
  RR 0.97 [0.9, 1.04]
  7 studies · 3640 participants
  Moderate

High levels of PEEP vs low levels of PEEP

• High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 2594 participants
  Low

High levels of PEEP vs low levels of PEEP

• High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 2309 participants
  Low

High levels of PEEP vs low levels of PEEP

• High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 1611 participants
  Moderate

High levels of PEEP vs low levels of PEEP

High levels of PEEP showed no clear difference in barotrauma compared with low levels of PEEP (low certainty).

• High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes only
  RR 1 [0.64, 1.57]
  9 studies · 3791 participants
  Low

High levels of PEEP vs low levels of PEEP

• High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1654 participants
  Low