Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Eyes and Vision

No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 6 · 85.7%Moderate 0 · 0%High 0 · 0%

Failure at 12 months ‐ primary trabeculectomy · wound healing in glaucoma surgery

MMC showed no clear difference in failure of functioning trabeculectomy at 1 year compared with 5‐FU (low certainty).

1 finding from 1 review

Mitomycin C versus 5‐Fluorouracil for wound healing in glaucoma surgery 2015 · Cochrane Headline outcomes only
RR 0.65 [0.19, 2.2]
11 studies · 634 participants
Low

Intraocular pressure ( · wound healing in glaucoma surgery

1 finding from 1 review

Mitomycin C versus 5‐Fluorouracil for wound healing in glaucoma surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 386 participants
Low

Visual loss of 2‐3+ lines of visual acuity · wound healing in glaucoma surgery

MMC showed no clear difference in loss of 2 or more lines of Snellen visual acuity at 1 year compared with 5‐FU (low certainty).

1 finding from 1 review

Mitomycin C versus 5‐Fluorouracil for wound healing in glaucoma surgery 2015 · Cochrane Headline outcomes only
RR 2 [0.53, 7.59]
5 studies · 328 participants
Low

Postoperative complications: late hypotony · wound healing in glaucoma surgery

MMC showed no clear difference in postoperative complications: late hypotony compared with 5‐FU (low certainty).

1 finding from 1 review

Mitomycin C versus 5‐Fluorouracil for wound healing in glaucoma surgery 2015 · Cochrane Headline outcomes only
RR 1.37 [0.41, 4.63]
4 studies · 211 participants
Low

Postoperative complications: choroidal detachment · wound healing in glaucoma surgery

MMC showed no clear difference in postoperative complications: choroidal detachment compared with 5‐FU (low certainty).

1 finding from 1 review

Mitomycin C versus 5‐Fluorouracil for wound healing in glaucoma surgery 2015 · Cochrane Headline outcomes only
RR 0.86 [0.45, 1.63]
8 studies · 494 participants
Low

Proportion of participants with endophthalmitis · wound healing in glaucoma surgery

MMC showed no clear difference in postoperative complications: endophthalmitis compared with 5‐FU (low certainty).

1 finding from 1 review

Mitomycin C versus 5‐Fluorouracil for wound healing in glaucoma surgery 2015 · Cochrane Headline outcomes only
RR 3.89 [0.44, 34.57]
4 studies · 315 participants
Low

Quality of life at 1 year · wound healing in glaucoma surgery

The review found no eligible studies for this question.

1 finding from 1 review

Mitomycin C versus 5‐Fluorouracil for wound healing in glaucoma surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found