Prostate cancer‐specific death5
It is very uncertain whether whole gland primary cryotherapy changes time to death from prostate cancer (absolute effects:… compared with external beam radiotherapy (EBRT) (very low certainty).
1 finding from 1 review
Quality of life ‐ urinary function
1 finding from 1 review
Quality of life ‐ bowel function
1 finding from 1 review
Quality of life ‐ sexual function
1 finding from 1 review
Major adverse events
It is very uncertain whether whole gland primary cryotherapy changes major adverse events compared with external beam radiotherapy (EBRT) (very low certainty).
1 finding from 1 review
Time to death from any cause (absolute effects: overall mortality)
It is very uncertain whether whole gland primary cryotherapy changes time to death from any cause (absolute effects: overall mortality) compared with external beam radiotherapy (EBRT) (very low certainty).
1 finding from 1 review
Secondary interventions for treatment failure ‐ not reported
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall survival · men with advanced prostate cancer
Non‐steroidal antiandrogen monotherapy probably leads to higher overall survival compared with LHRH agonists or surgical castration monotherapy (moderate certainty).
1 finding from 1 review
Clinical progression · men with advanced prostate cancer
Non‐steroidal antiandrogen monotherapy probably leads to higher clinical progression compared with LHRH agonists or surgical castration monotherapy (moderate certainty).
1 finding from 1 review
Treatment failure · men with advanced prostate cancer
Non‐steroidal antiandrogen monotherapy probably leads to higher treatment failure compared with LHRH agonists or surgical castration monotherapy (moderate certainty).
1 finding from 1 review
Breast pain · men with advanced prostate cancer
Non‐steroidal antiandrogen monotherapy probably leads to higher breast pain compared with LHRH agonists or surgical castration monotherapy (moderate certainty).
1 finding from 1 review
Gynaecomastia · men with advanced prostate cancer
Non‐steroidal antiandrogen monotherapy probably leads to higher gynaecomastia compared with LHRH agonists or surgical castration monotherapy (moderate certainty).
1 finding from 1 review
Hot flashes · men with advanced prostate cancer
Non‐steroidal antiandrogen monotherapy probably leads to lower hot flashes compared with LHRH agonists or surgical castration monotherapy (moderate certainty).
1 finding from 1 review
Intervention not reported
Time to initiation of first subsequent therapy This outcome was not reported as a time‐to‐event outcome. Instead, authors of the trials reported the number of participants who received subsequent anticancer therapy after discontinuation of trial t... · people with a confirmed diagnosis of advanced renal cell carcinoma (combined risk groups) without previous systemic anticancer therapy
The intervention may leads to lower time to initiation of first subsequent therapy This outcome was not… (low certainty).
1 finding from 1 review
Prostatitis symptoms · participants with chronic prostatitis/chronic pelvic pain syndrome
1 finding from 1 review
Prostatitis symptoms: 'responders' Number of participants with a 25% or 6‐point decrease in NIH‐CPSI scores · participants with chronic prostatitis/chronic pelvic pain syndrome
Phytotherapy probably leads to higher prostatitis symptoms: 'responders' Number of participants with a 25%… compared with placebo or other agents (moderate certainty).
1 finding from 1 review
Adverse events · participants with chronic prostatitis/chronic pelvic pain syndrome
Phytotherapy showed no clear difference in adverse events compared with placebo or other agents (low certainty).
1 finding from 1 review
Sexual dysfunction ‐ not reported · participants with chronic prostatitis/chronic pelvic pain syndrome
1 finding from 1 review
Quality of life ‐ not reported · participants with chronic prostatitis/chronic pelvic pain syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Depression and anxiety ‐ not reported · participants with chronic prostatitis/chronic pelvic pain syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found