Low molecular weight heparin vs unfractionated heparin
Extracorporeal circuit thrombosis Median · adults with kidney failure treated with long‐term HD
1 finding from 1 review
- 1.58 [0.46, 5.42]3 studies · 91 participantsLow
Findings
What do systematic reviews say?
14 questions · 14 findings · 2 reviews · Kidney and Transplant
No studies found 5 · 35.7%GRADE not reported 0 · 0%Very low 3 · 21.4%Low 6 · 42.9%Moderate 0 · 0%High 0 · 0%
Low molecular weight heparin vs unfractionated heparin
Major bleeding · adults with kidney failure treated with long‐term HD
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Low molecular weight heparin vs unfractionated heparin
Death (any cause) (median · adults with kidney failure treated with long‐term HD
Low molecular weight heparin showed no clear difference in death (any cause) Median compared with unfractionated heparin (low certainty).
1 finding from 1 review
- RR 2.64 [0.51, 13.83]3 studies · 120 participantsLow
Low molecular weight heparin vs unfractionated heparin
Dialysis vascular access thrombosis Median · adults with kidney failure treated with long‐term HD
Low molecular weight heparin showed no clear difference in dialysis vascular access thrombosis Median compared with unfractionated heparin (low certainty).
1 finding from 1 review
- RR 0.2 [0.01, 3.7]2 studies · 45 participantsLow
Low molecular weight heparin vs unfractionated heparin
Dialysis vascular adequacy (Kt/V) · adults with kidney failure treated with long‐term HD
1 finding from 1 review
- no estimate extracted1 study · 20 participantsLow
Low molecular weight heparin vs unfractionated heparin
Minor bleeding · adults with kidney failure treated with long‐term HD
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Low molecular weight heparin vs unfractionated heparin
Blood transfusion · adults with kidney failure treated with long‐term HD
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Unfractionated heparin vs low molecular weight heparin
Successful prevention of clotting · CRRT
It is very uncertain whether unfractionated heparin changes successful prevention of clotting compared with low molecular weight heparin (very low certainty).
1 finding from 1 review
- Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes onlyRR 0.95 [0.7, 1.31]1 study · 54 participantsVery low
Unfractionated heparin vs low molecular weight heparin
Treatment cessation due to adverse events · CRRT
Unfractionated heparin showed no clear difference in treatment cessation due to adverse events compared with low molecular weight heparin (low certainty).
1 finding from 1 review
- Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes onlyRR 0.29 [0.02, 3.53]2 studies · 77 participantsLow
Unfractionated heparin vs low molecular weight heparin
Recovery of kidney function · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
- Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Unfractionated heparin vs low molecular weight heparin
Thrombocytopenia · CRRT
It is very uncertain whether unfractionated heparin changes thrombocytopenia compared with low molecular weight heparin (very low certainty).
1 finding from 1 review
- Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes onlyRR 0.57 [0.2, 1.63]2 studies · 124 participantsVery low
Unfractionated heparin vs low molecular weight heparin
Cost to health care services · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
- Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Unfractionated heparin vs low molecular weight heparin
Major bleeding · CRRT
Unfractionated heparin showed no clear difference in major bleeding compared with low molecular weight heparin (low certainty).
1 finding from 1 review
- Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes onlyRR 0.58 [0.13, 2.58]5 studies · 153 participantsLow
Unfractionated heparin vs low molecular weight heparin
Death: unknown time frame · CRRT
It is very uncertain whether unfractionated heparin changes death: unknown time frame compared with low molecular weight heparin (very low certainty).
1 finding from 1 review
- Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes onlyRR 0.78 [0.51, 1.18]1 study · 29 participantsVery low