Cochrane · systematic review · CD011858
Anticoagulation for people receiving long‐term haemodialysis
Natale, P, Palmer, SC, Ruospo, M, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Low molecular weight heparin versus unfractionated heparin for haemodialysis‐related anticoagulation
Population: adults with kidney failure treated with long‐term HD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Extracorporeal circuit thrombosis Median Low molecular weight heparin vs unfractionated heparin | 1.58 [0.46, 5.42] | 3 studies · 91 participants | Low Downgraded: risk of bias |
Major bleeding Median Low molecular weight heparin vs unfractionated heparin | no estimate extracted | NR | No studies |
Death (any cause) Median Low molecular weight heparin vs unfractionated heparin | RR 2.64 [0.51, 13.83] | 3 studies · 120 participants | Low Downgraded: risk of bias |
Dialysis vascular access thrombosis Median Low molecular weight heparin vs unfractionated heparin | RR 0.2 [0.01, 3.7] | 2 studies · 45 participants | Low Downgraded: risk of bias |
Dialysis vascular adequacy (Kt/V) Low molecular weight heparin vs unfractionated heparin | no estimate extracted | 1 study · 20 participants | Low Downgraded: risk of bias |
Minor bleeding Median Low molecular weight heparin vs unfractionated heparin | no estimate extracted | NR | No studies |
Blood transfusion Low molecular weight heparin vs unfractionated heparin | no estimate extracted | NR | No studies |