What do systematic reviews say?

LDL‐cholesterol · Participants with normal or elevated blood pressure, but otherwise healthy

Systolic blood pressure · adult participants

Diastolic blood pressure · adult participants

Heart rate · adult participants

Total mortality · adults with primary hypertension

Stroke · adults with primary hypertension

Total coronary heart disease · adults with primary hypertension

Cardiovascular events · adults with primary hypertension

Withdrawals due to adverse events · adults with primary hypertension

Angiotensin receptor blocker (medium‐ versus low‐dose) · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

High‐ versus low‐dose · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

Medium‐ versus low‐dose · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

High‐ versus low‐dose · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

Medium‐ versus low‐dose · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

High‐ versus low‐dose · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

Medium‐ versus low‐dose · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

Angiotensin receptor blocker (high‐ versus low‐dose) · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

White population, normotensive, SBP mmHg · White population with normal or elevated blood pressure, but otherwise healthy

Asian population, normotensive, DBP mmHg · Asian population with normal or elevated blood pressure, but otherwise healthy

Asian population, hypertensive, SBP mmHg · Asian population with normal or elevated blood pressure, but otherwise healthy