What do systematic reviews say?

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

Longer intervals (5‐15 days) (intervention) showed no clear difference in catheter‐related blood stream infection (CRBSI) compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

• Frequency of dressing changes for central venous access devices on catheter‐related infections 2016 · Cochrane Headline outcomes only
  RR 1.42 [0.4, 4.98]
  Studies not reported
  Low

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

Longer intervals (5‐15 days) (intervention) showed no clear difference in all‐cause mortality compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

• Frequency of dressing changes for central venous access devices on catheter‐related infections 2016 · Cochrane Headline outcomes only
  RR 1.06 [0.9, 1.25]
  Studies not reported
  Low

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

• Frequency of dressing changes for central venous access devices on catheter‐related infections 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

Longer intervals (5‐15 days) (intervention) showed no clear difference in pain № of participants: 193 (2 RCTs) compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

• Frequency of dressing changes for central venous access devices on catheter‐related infections 2016 · Cochrane Headline outcomes only
  RR 0.8 [0.46, 1.38]
  Studies not reported
  Low