Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Oral medicine and oral cancer

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Daily chewing gum for 2 weeks or longer vs No gum chewing or control

Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

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1 finding from 1 review

The effect of gum chewing on xerostomia and salivary flow rate in elderly and medically compromised subjects: a… 2023 All outcomes
2 to 12 weeks · Meta-regression slope for change in standardized salivary flow rate per additional week of chewing · Meta-regression by chewing duration
SMD per week 0.06
6 studies · 291 participants
GRADE not reported

Epidermal growth factor (EGF), oral spray vs placebo

Interruptions to cancer treatment (radiotherapy breaks longer than two days) · Adults with cancer receiving treatment

Epidermal growth factor (EGF), oral spray showed no clear difference in interruptions to cancer treatment (radiotherapy breaks longer than… compared with placebo; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors 2017 · Cochrane All outcomes
Radiotherapy to the head and neck
RR 4.38 [0.25, 75.44]
1 study · 113 participants
GRADE not reported