Findings

What do systematic reviews say?

21 questions · 24 findings · 2 reviews · Pregnancy and Childbirth

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No studies found 7 · 29.2%GRADE not reported 2 · 8.3%Very low 7 · 29.2%Low 5 · 20.8%Moderate 3 · 12.5%High 0 · 0%

Laxative vs placebo

Pain or straining on defecation · women in the postpartum period

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laxative vs placebo

Adverse effects on babies: loose stools · women in the postpartum period

It is very uncertain whether laxative changes adverse effects on babies: loose stools compared with placebo (very low certainty).

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 0.62 [0.16, 2.41]
1 study · 281 participants
Very low

Laxative vs placebo

Adverse effects on babies: diarrhoea · women in the postpartum period

It is very uncertain whether laxative changes adverse effects on babies: diarrhoea compared with placebo (very low certainty).

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 2.46 [0.23, 26.82]
1 study · 281 participants
Very low

Laxative vs placebo

Incidence of postpartum constipation · women in the postpartum period

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laxative vs placebo

Quality of life · women in the postpartum period

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laxative vs placebo

Time to first BM (№ women with 1st BM on day 1 after delivery) · women in the postpartum period

Laxative may leads to higher time to first bowel movement (BM) (№ women with 1st BM less than 24… compared with placebo (low certainty).

2 findings from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 2.9 [2.24, 3.75]
1 study · 471 participants
Low
Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 0.94 [0.72, 1.22]
1 study · 471 participants
Very low

Laxative vs placebo

Time to first BM (№ women with 1st BM on day 2 after delivery) · women in the postpartum period

Laxative may leads to lower time to first BM (№ women with 1st BM on day 2 after delivery) compared with placebo (low certainty).

3 findings from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 0.23 [0.11, 0.45]
1 study · 471 participants
Low
Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 0.05 [0, 0.89]
1 study · 471 participants
Low
Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 0.22 [0.03, 1.87]
1 study · 471 participants
Very low

Laxative vs placebo

Adverse effects on women: abdominal cramps · women in the postpartum period

Laxative may leads to higher adverse effects on women: abdominal cramps compared with placebo (low certainty).

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 4.23 [1.75, 10.19]
1 study · 471 participants
Low

Stimulant laxatives vs bulk‐forming laxatives

Primary outcome ‐ constipation improvement · women with treating constipation in pregnancy

Stimulant laxatives probably leads to higher primary outcome ‐ constipation improvement compared with bulk‐forming laxatives (moderate certainty).

1 finding from 1 review

Interventions for treating constipation in pregnancy 2015 · Cochrane Headline outcomes only
RR 1.59 [1.21, 2.09]
1 study · 140 participants
Moderate

Stimulant laxatives vs bulk‐forming laxatives

Primary outcome ‐ pain on defecation ‐ not reported · women with treating constipation in pregnancy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating constipation in pregnancy 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Stimulant laxatives vs bulk‐forming laxatives

Frequency of defecation (mean number of bowel movements per week) · women with treating constipation in pregnancy

1 finding from 1 review

Interventions for treating constipation in pregnancy 2015 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 2 participants
GRADE not reported

Stimulant laxatives vs bulk‐forming laxatives

Stool consistency · women with treating constipation in pregnancy

1 finding from 1 review

Interventions for treating constipation in pregnancy 2015 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 2 participants
GRADE not reported

Stimulant laxatives vs bulk‐forming laxatives

Secondary outcome ‐ abdominal discomfort · women with treating constipation in pregnancy

Stimulant laxatives probably leads to higher secondary outcome ‐ abdominal discomfort compared with bulk‐forming laxatives (moderate certainty).

1 finding from 1 review

Interventions for treating constipation in pregnancy 2015 · Cochrane Headline outcomes only
RR 2.33 [1.15, 4.73]
1 study · 140 participants
Moderate

Stimulant laxatives vs bulk‐forming laxatives

Diarrhoea · women with treating constipation in pregnancy

Stimulant laxatives may leads to higher secondary outcome ‐ diarrhoea compared with bulk‐forming laxatives (low certainty).

1 finding from 1 review

Interventions for treating constipation in pregnancy 2015 · Cochrane Headline outcomes only
RR 4.5 [1.01, 20.09]
1 study · 140 participants
Low

Stimulant laxatives vs bulk‐forming laxatives

Secondary outcome ‐ women's satisfaction · women with treating constipation in pregnancy

Stimulant laxatives showed no clear difference in secondary outcome ‐ women's satisfaction compared with bulk‐forming laxatives (moderate certainty).

1 finding from 1 review

Interventions for treating constipation in pregnancy 2015 · Cochrane Headline outcomes only
RR 1.06 [0.77, 1.46]
1 study · 140 participants
Moderate

Laxative plus bulking agent vs laxative alone

Pain or straining on defecation · postpartum women who underwent surgical repair of third degree perineal tears

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 147 participants
Very low

Laxative plus bulking agent vs laxative alone

Incidence of postpartum constipation · postpartum women who underwent surgical repair of third degree perineal tears

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laxative plus bulking agent vs laxative alone

Quality of life · postpartum women who underwent surgical repair of third degree perineal tears

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laxative plus bulking agent vs laxative alone

Time from completion of operation to first bowel movement (hours) · postpartum women who underwent surgical repair of third degree perineal tears

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 147 participants
Very low

Laxative plus bulking agent vs laxative alone

Adverse effects on women: faecal incontinence during first 10 postpartum days · postpartum women who underwent surgical repair of third degree perineal tears

It is very uncertain whether laxative plus bulking agent changes adverse effects on women: faecal incontinence during first 10… compared with laxative alone (very low certainty).

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 1.81 [1.01, 3.23]
1 study · 147 participants
Very low