Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

52 questions · 52 findings · 9 reviews · Pregnancy and Childbirth

No studies found 14 · 26.9%GRADE not reported 4 · 7.7%Very low 11 · 21.2%Low 15 · 28.8%Moderate 8 · 15.4%High 0 · 0%

Lifestyle vs control ‐ Neonatal and later outcomes

Perinatal (fetal and neonatal death) and later infant mortality · women with gestational diabetes mellitus

Lifestyle showed no clear difference in perinatal (fetal and neonatal death) and later infant mortality compared with control ‐ Neonatal and later outcomes (low certainty).

1 finding from 1 review

Lateral postures vs other postures

Severe perineal tears (3rd degree or higher, as defined by trialists) · fetal malposition in labour

It is very uncertain whether lateral postures changes severe perineal tears (3rd degree or higher, as defined by trialists) compared with other postures (very low certainty).

1 finding from 1 review

Lateral postures vs other postures

Maternal satisfaction (as defined by trialists using standardised tools available) · fetal malposition in labour

Lateral postures showed no clear difference in maternal satisfaction (as defined by trialists using standardised… compared with other postures (low certainty).

1 finding from 1 review

Lateral postures vs other postures

Serious neonatal morbidity (composite outcome defined as death, admission to neonatal intensive care, neonatal encephalopathy, or as defined by trialists) · fetal malposition in labour

It is very uncertain whether lateral postures changes serious neonatal morbidity (composite outcome defined as death,… compared with other postures (very low certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Death (fetal, neonatal, or later (up to 2 years' corrected age))** · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death (fetal, neonatal, or later (up to 2 years' corrected age))** compared with placebo (outcomes (moderate certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Death (fetal, neonatal, or later (up to school age))** · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death (fetal, neonatal, or later (up to school age))** compared with placebo (outcomes (low certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D1: Total deaths (after randomisation) up to mid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D1: Total deaths (after randomisation) up to mid‐ to later childhood compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D2: Neurocognitive impairment atmid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D2: Neurocognitive impairment atmid‐ to later childhood compared with single course (low certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

D3: Survival free of neurocognitive impairment atmid‐ to later childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D3: Survival free of neurocognitive impairment atmid‐ to later… compared with single course (moderate certainty).

1 finding from 1 review